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Archives for September–December 2023

High Variability in ICU Transfusion Practices Globally

The International Point Prevalence Study of Intensive Care Unit Transfusion Practices (InPUT) is a prospective cohort study that included 3643…

October 18, 2023

AABB Clinical Practice Guidelines for RBC Transfusions

The AABB has updated their clinical practice guidelines regarding RBC transfusion thresholds.  The guidelines are based on data from 45…

October 12, 2023

Induced Abortion Does Not Increase Rh Alloimmunization

Rh immunoglobulin routinely given to Rh-negative pregnant women during the second and third trimesters has reduced the maternal Rh sensitization…

October 4, 2023

Pathogen-Reduced Platelet Use and Overall Blood Product Cost Increased

Since 1997, the biennial Department of Health and Human Services’ National Blood and Collection Utilization Survey (NBCUS) has been used…

September 27, 2023

A Possible Link between RBC Transfusions and Brain Amyloidosis?

Cerebral amyloid angiopathy (CAA) has multiple etiologies but is characterized by deposits of misfolded amyloid β peptides and is the…

September 20, 2023

Recombinant von Willebrand Factor and Tranexamic Acid for Menstruating Women with von Willebrand Disease

Von Willebrand disease is an inherited bleeding disorder affecting about 0.1% of the population.  Von Willebrand disease is caused by…

September 13, 2023

Concizumab Lowers Rate of Bleeding in Hemophilia Patients with Inhibitors

While current guidelines for treating patients with hemophilia A or B recommend intravenous factor VIII or IX concentrates, many patients…

September 6, 2023

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