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Archives for September–December 2024

Liberal Transfusion Thresholds for Patients with Acute Brain Injury

Over the past 25 years, >45 randomized clinical trials have shown that a restrictive transfusion strategy is best for most…

October 17, 2024

RBCs Regulate Hemostasis Through Platelet-Dependent and -Independent Mechanisms

Red blood cells (RBCs) deliver oxygen to tissues and also contribute to hemostasis and thrombosis through platelet interactions that promote…

October 9, 2024

Liberal Transfusion Threshold of 9-10 g/dL for Patients with Myocardial Infarction

While restrictive transfusion hemoglobin (Hb) thresholds are appropriate for most patients, those with anemia and myocardial infarction (MI) may benefit…

October 2, 2024

Genetic Background of AnWj-Negative Blood Group Deciphered

Of the 45 blood group systems comprising 362 described antigens, only a few high prevalence antigens are not genetically resolved…

September 25, 2024

Donor-Specific Antibody Levels and Platelet Transfusion Response Among Refractory Patients

  Hematology-oncology patients often require multiple platelet transfusions, which can lead to immune-mediated platelet transfusion refractoriness. This condition may necessitate…

September 19, 2024

Global Blood Supply Challenges

The World Health Organization (WHO) considers blood an essential medicine, yet nearly two-thirds of countries—primarily low- and middle-income countries (LMIC)—lack…

September 11, 2024

Prevalence and Trends of Maternal RBC Alloimmunization in the U.S.

Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic…

September 4, 2024

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