Global Burden of Sickle Cell Anemia A modeling study published in the journal Plos Medicine suggests that the global burden of sickle cell anemia (SCA) is… July 26, 2013
Preoperative Transfusion Beneficial for Patients with Sickle Cell Disease A multicenter randomized trial suggests that preoperative transfusion is associated with decreased perioperative complications among patients with sickle cell disease… February 22, 2013
HLA-haploidentical Bone Marrow Transplantation May be Alternative Cure for Sickle Cell Patients Researchers have shown that bone marrow transplantation using related HLA-haploidentical donors may be a safe and effective cure for sickle… December 7, 2012
Babesia Infection Reduces Red Cell Deformability The United States reports the highest number of Babesia infections globally. Babesia, a tick-borne pathogen related to the malaria parasite,… May 14, 2025
Racial Differences in Red Blood Cell Transfusions Transfusion guidelines recommend transfusing red blood cells (RBCs) when hemoglobin (Hb) levels drop below 7 or 8 g/dL, but variation… August 3, 2022
Universal Donor Red Blood Cells Can Be Genetically Engineered Using CRISPR Gene Editing Alloimmunization commonly affects 2-5% of all transfusion recipients and approximately 30% of chronically transfused patients with sickle-cell disease. Since ABO… May 2, 2018
Age of Red Blood Cells Does Not Affect Lactic Acidosis Although a recent meta-analysis of randomized trials has reported no difference in adverse events based on the age of the… December 11, 2015
VIDEO: Red Cell Alloimmunization Two studies and an editorial published in the journal Transfusion discuss red cell alloimmunization among patients with sickle cell disease… April 15, 2013
Female Sex is not an Independent Risk Factor for Red Blood Cell Alloimmunization Researchers from the Sanquin-LUMC in the Netherlands have concluded that female sex alone is not sufficient to recommend extended crossmatching… October 5, 2012
Phosphatidylserine and Phosphatidylethanolamine Levels on RBCs Important for Transfusion Outcomes Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are phospholipids that normally reside in the inner leaflet of the red blood cell membrane…. December 10, 2025
