Pathogenesis of Antibody-Mediated TRALI by Complement Transfusion-related acute lung injury (TRALI) is a rare, life-threatening adverse transfusion reaction that is difficult to predict and treat. The… January 25, 2024
Annual U.K. SHOT Report on Serious Hazards of Transfusions The Royal College of Pathologists in the United Kingdom recently published their annual report for 2022 on the Serious Hazards… July 26, 2023
Intracellular RBC Antigens Can Enhance RBC Alloimmunization in Mice RBC alloimmunization from transfusions or pregnancy can be life threatening. Currently, scientists have identified 43 polymorphic RBC surface antigen systems,… June 14, 2023
Risk Factors for Allergic Transfusion Reactions in Pediatric Patients Allergic transfusion reactions (ATRs) are common and can range from mild to severe. Younger age, hematological/oncological disease, increasing number of… May 17, 2022
X- and Gamma-Irradiation Impact Red Blood Cells Similarly Transfusion-associated graft versus host disease (TA-GVHD) is a rare complication that occurs when histoincompatible viable lymphocytes are transfused into an… November 22, 2021
T helper Cells and Alloimmunization in Patients with Sickle Cell Disease Alloimmunization can lead to life-threatening hemolytic transfusion reactions and make it difficult to find compatible blood. While it is unknown… March 16, 2021
Antigen Density on Surface of RBCs a Factor in RBC Clearance in Incompatible Transfusions Select patients with chronic anemia and sickle cell disease require recurrent transfusions and are at risk for alloimmunization and potentially… February 3, 2021
NT-proBNP Levels May Help Diagnose TACO and TRALI Distinguishing between transfusion-associated circulatory overload (TACO), transfusion-related acute lung injury (TRALI), and other pulmonary transfusion reactions, including transfused-associated acute respiratory… December 9, 2020
Convalescent Plasma for COVID-19 Safe in First 5,000 Patients With limited therapies for patients with COVID-19 and a mortality rate of approximately 50% for patients in the ICU, demand… May 19, 2020
National Survey Finds Stable Adverse Transfusion Reaction Rate in the U.S. The 2017 National Blood Collection and Utilization Survey (NBCUS) used a web-based survey of approximately 3,000 U.S. community-based and hospital-based… March 11, 2020