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Adverse Events (non-infectious)

Locus on Chromosome 5 Associated with Alloimmunization

Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with…

January 9, 2019

Electronic Scanning of Patient Wristbands Reduces Chance of ABO-Incompatible Transfusions

ABO-incompatible transfusions can be life-threatening to patients and are often attributable to human errors. Wrong blood in tube (WBIT) errors…

December 19, 2018

Older RBCs Associated with Increased Risk of Death Among Trauma Patients

Current regulations allow red blood cells (RBCs) to be stored and used for up to 42 days. During this time,…

November 27, 2018

Matching RH Genotypes for Patients with Sickle Cell Disease

RH antigens are encoded by two highly polymorphic genes, RHD and RHCE.  Homologous recombination and novel polymorphism have resulted in…

September 19, 2018

Restrictive Transfusion Strategy for Cardiac Surgery Patients

Previous studies have reported that restrictive transfusion strategies are non-inferior compared to liberal strategies for cardiac surgery patients followed up…

August 30, 2018

Perioperative RBC Transfusions Linked to Increased Risk of Blood Clots

Venous thromboembolism (VTE) is associated with 5-10% of all hospital deaths, or about 100,000 to 200,000 deaths each year in…

June 20, 2018

New Assessment Criteria to Diagnose and Manage Delayed Hemolytic Transfusion Reactions in Sickle Cell Patients

Many patients with sickle cell disease (SCD) require chronic transfusions and are at risk for life-threatening delayed hemolytic transfusion reactions…

May 23, 2018

Transfusion-Associated Circulatory Overload (TACO) Difficult to Diagnosis in Children

Transfusion-associated circulatory overload (TACO) is currently one of the leading causes of transfusion-related deaths even though it is often underdiagnosed…

March 28, 2018

Transfusion Patients with Hereditary Hemorrhagic Telangiectasia Have Increased Risk of Alloimmunization

Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is an autosomal dominate disorder characterized by arteriovenous malformations. In patients…

March 7, 2018

Alloimmunization to One RBC Antigen Triggers Alloimmunization to Other RBC Antigens

The risk of alloimmunization to polymorphic RBC antigens is high for individuals who undergo chronic transfusion therapy.  Researchers recently utilized…

January 31, 2018

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