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Adverse Events (non-infectious)

National Survey Finds Stable Adverse Transfusion Reaction Rate in the U.S.

The 2017 National Blood Collection and Utilization Survey (NBCUS) used a web-based survey of approximately 3,000 U.S. community-based and hospital-based…

March 11, 2020

Risk Factors for Hyperhemolysis Syndrome Identified

Hyperhemolysis Syndrome (HS) is a rare, potentially fatal condition characterized by the development of severe anemia after transfusion in which…

October 16, 2019

Increased Risk of Transfusion Reactions in Postpartum Blood Transfusions

Transfusion reactions occur in 0.15% to 3.7% of all transfusions and can range from mild fevers to severe, life-threatening reactions….

August 28, 2019

The Role of Osteopontin in Murine TRALI

Osteopontin (OPN) is a proinflammatory, multifunctional protein with both physiological and pathological roles. Since OPN attracts neutrophils, which are involved…

July 11, 2019

New Criteria for Transfusion-Associated Circulatory Overload (TACO)

  Transfusion-associated circulatory overload (TACO) is one of the major causes of death associated with transfusions. TACO is characterized by…

May 21, 2019

Delayed Hemolytic Transfusion Reactions are Under Diagnosed in Patients with Sickle Cell Disease

Red blood cell transfusions are often used to treat patients with sickle cell disease (SCD), and these patients are at…

May 1, 2019

Locus on Chromosome 5 Associated with Alloimmunization

Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with…

January 9, 2019

Electronic Scanning of Patient Wristbands Reduces Chance of ABO-Incompatible Transfusions

ABO-incompatible transfusions can be life-threatening to patients and are often attributable to human errors. Wrong blood in tube (WBIT) errors…

December 19, 2018

Older RBCs Associated with Increased Risk of Death Among Trauma Patients

Current regulations allow red blood cells (RBCs) to be stored and used for up to 42 days. During this time,…

November 27, 2018

Matching RH Genotypes for Patients with Sickle Cell Disease

RH antigens are encoded by two highly polymorphic genes, RHD and RHCE.  Homologous recombination and novel polymorphism have resulted in…

September 19, 2018

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