Genetic Variation in the Fc-gamma Receptor Gene is Associated with Protection against RBC Alloimmunization Genetic variation in the Fc-ɣ receptor gene has been shown to be associated with some auto- and alloimmune diseases. Researchers… November 16, 2017
Trying to Decipher Relationship between Previously Pregnant Donors and RBC Transfusion-related Mortality Although blood from previously pregnant female donors has been shown to be associated with transfusion-related acute lung injury (TRALI), the… October 25, 2017
Bedside Checklists Could Prevent Most ABO-Incompatible Transfusions and Other Adverse Events Since 1996, the hemovigilance surveillance system in the United Kingdom has collected and published yearly reports on the serious hazards… August 16, 2017
Patients with Hematologic Cancers Have Lower Rates of Alloimmunization with RhD Over 20% of RhD-negative non-oncology patients exposed to RhD-positive red blood cells (RBCs) become alloimmunized to the RhD antigen. In… February 22, 2017
KEL-Antigen Modulation is Important for Anti-KEL Immunoprophylaxis Rh immunoglobulin therapy has been used for more than 60 years to prevent alloimmunization in Rh-negative pregnant women carrying an… January 5, 2017
Eculizumab Treatment May Be Beneficial For Treating Hemolysis Transfusion Reactions in Patients with Sickle Cell Disease Delayed hemolytic transfusion reactions (DHTR) in patients with sickle cell disease can lead to multiple organ failure and may be… March 2, 2016
Chronic Lymphocytic Leukemia is not Transmitted through Transfusions Monoclonal B-cell lymphocytosis (MBL), a precursor of chronic lymphocytic leukemia (CLL), can be present in healthy blood donors. This raises… November 6, 2015
FDA Reports Safest Blood Supply in History In the Fatalities Reported to the FDA Following Blood Collection and Transfusion: Annual Summary for Fiscal Year 2014, the FDA… September 11, 2015
Donor Lymphocytes May Play a Large Role in Transfusion-Associated Graft-Versus-Host Disease Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare, but fatal complication of blood transfusions. TA-GVHD occurs when donor lymphocytes, not recognized… July 31, 2015
VIDEO: Innovative Ways to Think About TRALI May Reduce Cases Today we’ll be discussing TRALI, or transfusion-related acute lung injury. A major cause of TRALI is donor antibodies to white… May 15, 2015
Adverse Events (non-infectious)