Patients with Hematologic Cancers Have Lower Rates of Alloimmunization with RhD Over 20% of RhD-negative non-oncology patients exposed to RhD-positive red blood cells (RBCs) become alloimmunized to the RhD antigen. In… February 22, 2017
KEL-Antigen Modulation is Important for Anti-KEL Immunoprophylaxis Rh immunoglobulin therapy has been used for more than 60 years to prevent alloimmunization in Rh-negative pregnant women carrying an… January 5, 2017
Eculizumab Treatment May Be Beneficial For Treating Hemolysis Transfusion Reactions in Patients with Sickle Cell Disease Delayed hemolytic transfusion reactions (DHTR) in patients with sickle cell disease can lead to multiple organ failure and may be… March 2, 2016
Chronic Lymphocytic Leukemia is not Transmitted through Transfusions Monoclonal B-cell lymphocytosis (MBL), a precursor of chronic lymphocytic leukemia (CLL), can be present in healthy blood donors. This raises… November 6, 2015
FDA Reports Safest Blood Supply in History In the Fatalities Reported to the FDA Following Blood Collection and Transfusion: Annual Summary for Fiscal Year 2014, the FDA… September 11, 2015
Donor Lymphocytes May Play a Large Role in Transfusion-Associated Graft-Versus-Host Disease Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare, but fatal complication of blood transfusions. TA-GVHD occurs when donor lymphocytes, not recognized… July 31, 2015
VIDEO: Innovative Ways to Think About TRALI May Reduce Cases Today we’ll be discussing TRALI, or transfusion-related acute lung injury. A major cause of TRALI is donor antibodies to white… May 15, 2015
VIDEO: Newly Formed US Hemovigilance System for Transfusions Reports Similar Adverse Reaction Rates to Other Countries Today we will be discussing a newly formed United States hemovigilance system that tracks adverse reactions related to transfusions. While… April 15, 2015
VIDEO: Platelet Transfusions Increase Risk of Death and Arterial Thrombosis among Patients with TTP and HIT Today we will be discussing risks associated with platelet transfusions for patients with rare, immune-mediated platelet consumptive disorders. Thrombotic thrombocytopenic… January 30, 2015
Liberal RBC Transfusions Do Not Increase Mortality It has been hypothesized that blood transfusions may lead to increased risk of subsequent infections, cancer, and possibly death. The… December 19, 2014
Adverse Events (non-infectious)