Cold-Stored Group O Whole Blood Use in Severely Injured Patients Trauma patients have a severe risk of hemorrhagic shock, and managing their platelet count is crucial for their survival. In… December 14, 2021
FDA Update about Bacterial Contamination of Platelets The United Stated Food and Drug Administration (FDA) issued guidance to reduce the risk of septic transfusion reactions associated with… December 8, 2021
RBC and Plasma Transfusions Decreased in the U.S. (2015-2018) Blood transfusions are one of the most common medical procedures in hospitalized patients, and robust data from randomized clinical trials… September 28, 2021
REDS-III Study Highlights Need for Pediatric Oncology Transfusion Guidelines Pediatric hematology/oncology patients receive a significant proportion of pediatric transfusions. Data, however, are limited guiding clinical decisions for transfusions… September 22, 2021
Convalescent Plasma Does Not Prevent Disease Progression in COVID-19 Emergency Room Patients Very few therapeutic options are available early in infectious disease epidemics with the exception of convalescent plasma. In August 2020,… August 24, 2021
Pilot Randomized Clinical Trial Finds No Benefit for Prophylactic Plasma Transfusions Annually, 2.4 million units of plasma are transfused in the U.S. Approximately a quarter to half of plasma transfusions are… July 27, 2021
HLA Induced Refractoriness to Platelet Transfusions Platelet transfusion refractoriness (PTR) is usually caused by non-immune platelet consumption but can also be caused by immune-mediated platelet destruction. … June 16, 2021
High Titer Convalescent Plasma Does Not Improve Survival of Hospitalized Patients with COVID-19 With few treatment options, more than 500,000 patients with COVID-19 were transfused with convalescent plasma in the United States. Observational… May 26, 2021
ABO-incompatible Platelet Transfusions and Platelet Recovery in Patients with Intracerebral Hemorrhage Historically, standard practice has been to provide ABO-compatible platelets when possible. However, since hemolysis is rare after single platelet transfusions… May 18, 2021
Tranexamic Acid To Reduce Blood Loss after Cesarean Delivery Tranexamic acid is a common antifibrinolytic drug used to prevent blood loss during surgeries and treat heavy menstrual cycles. Several… May 5, 2021