Covid-19 Convalescent Plasma Neutralizes Variants of Concern Including Omicron Recent omicron variants of the SARS-CoV-2 virus have at least 32 changes in the spike protein relative to the original… March 9, 2022
Hospitalized COVID-19 Patients with Early Disease and Preexisting Conditions May Benefit from Convalescent Plasma Understanding which patients with COVID-19 benefit the most from COVID-19 convalescent plasma (CCP) may help determine how convalescent plasma may… February 2, 2022
Outpatient COVID-19 Convalescent Plasma Reduces Hospitalizations While more than 500,000 units of COVID-19 convalescent plasma (CCP) have been transfused in the United States alone, the use… December 21, 2021
Cold-Stored Group O Whole Blood Use in Severely Injured Patients Trauma patients have a severe risk of hemorrhagic shock, and managing their platelet count is crucial for their survival. In… December 14, 2021
FDA Update about Bacterial Contamination of Platelets The United Stated Food and Drug Administration (FDA) issued guidance to reduce the risk of septic transfusion reactions associated with… December 8, 2021
RBC and Plasma Transfusions Decreased in the U.S. (2015-2018) Blood transfusions are one of the most common medical procedures in hospitalized patients, and robust data from randomized clinical trials… September 28, 2021
REDS-III Study Highlights Need for Pediatric Oncology Transfusion Guidelines Pediatric hematology/oncology patients receive a significant proportion of pediatric transfusions. Data, however, are limited guiding clinical decisions for transfusions… September 22, 2021
Convalescent Plasma Does Not Prevent Disease Progression in COVID-19 Emergency Room Patients Very few therapeutic options are available early in infectious disease epidemics with the exception of convalescent plasma. In August 2020,… August 24, 2021
Pilot Randomized Clinical Trial Finds No Benefit for Prophylactic Plasma Transfusions Annually, 2.4 million units of plasma are transfused in the U.S. Approximately a quarter to half of plasma transfusions are… July 27, 2021
HLA Induced Refractoriness to Platelet Transfusions Platelet transfusion refractoriness (PTR) is usually caused by non-immune platelet consumption but can also be caused by immune-mediated platelet destruction. … June 16, 2021
Coagulation & Plasma Transfusion