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Archive by Topic » News

Typing Blood Group Variants from Whole-Genome Sequencing Data

Serological testing for ABO and RhD blood group compatibility has been standard practice for at least 60 years. ABO and…

May 30, 2018

New Assessment Criteria to Diagnose and Manage Delayed Hemolytic Transfusion Reactions in Sickle Cell Patients

Many patients with sickle cell disease (SCD) require chronic transfusions and are at risk for life-threatening delayed hemolytic transfusion reactions…

May 23, 2018

WBC Alloimmunization Infrequent in Granulocyte Transfusions

Neutropenia is characterized by abnormally low counts of neutrophils and is a common condition among patients receiving chemotherapy or hematopoietic…

May 16, 2018

Revisiting Zika virus screening for donated blood

In 2015, the Zika virus (ZIKV) rapidly spread to the Americas and other countries, and four possible transfusion-transmission cases were…

May 10, 2018

Universal Donor Red Blood Cells Can Be Genetically Engineered Using CRISPR Gene Editing

Alloimmunization commonly affects 2-5% of all transfusion recipients and approximately 30% of chronically transfused patients with sickle-cell disease. Since ABO…

May 2, 2018

Gene Therapy for β-Thalassemia Patients who Are Transfusion Dependent

β-thalassemia is one of the most common genetic diseases—especially in North Africa, the Middle East and Asia.  About 60-80% of…

April 25, 2018

Zika Virus RNA Can Shed for More Than 6 Months in Semen from Some Infected Men

The Zika virus (ZIKV), which has now spread to at least 48 countries including the United States, is associated with…

April 18, 2018

Costs are High for Administrating Blood Transfusions

A recent micro-costing study in the United Kingdom suggests administration costs are high for blood transfusions. Researchers collected detailed data…

April 11, 2018

Secondary Bacterial Culture for Platelets Reduces Transfusion Risk and Complies with FDA Draft Guidance for Platelet Safety

Platelets are most susceptible to bacterial contamination due to their storage conditions. In order to decrease the risk of bacterial…

April 4, 2018

Transfusion-Associated Circulatory Overload (TACO) Difficult to Diagnosis in Children

Transfusion-associated circulatory overload (TACO) is currently one of the leading causes of transfusion-related deaths even though it is often underdiagnosed…

March 28, 2018

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