FDA Approves CAR-T Gene Therapy for Acute Lymphoblastic Leukemia With the FDA approval of the first gene therapy, or a nucleic acid drug, we have entered a new era… September 7, 2017
Leukoreduction of Platelet Units Followed by Mirasol Pathogen Reduction May Prevent Alloimmunization Alloimmunization to donor platelets is common in transfused, immunosuppressed oncology patients. Leukoreduction reduces alloimmunization by more than half. Researchers recently… August 30, 2017
Intravenous Immunoglobulin Treatment for Patients with Heparin-Induced Thrombocytopenia Patients Unresponsive to Standard Treatment Heparin-induced thrombocytopenia (HIT) is a severe complication of heparin treatment with significant risks of morbidity and mortality. HIT is caused… August 23, 2017
Bedside Checklists Could Prevent Most ABO-Incompatible Transfusions and Other Adverse Events Since 1996, the hemovigilance surveillance system in the United Kingdom has collected and published yearly reports on the serious hazards… August 16, 2017
Negligible Risk of Transfusion-Transmitted Creutzfeldt Jakob Disease Creutzfeldt Jakob Disease (CJD) is a fatal and rapidly progressing neurodegenerative disorder caused by misfolded proteins, or prions, in the… August 10, 2017
Low ADAMTS13 antigen and high ADAMTS13 antibody levels associated with mortality in TTP patients While thrombotic thrombocytopenic purpura (TTP) has a mortality rate of approximately 10% even when treated, predictors of mortality are unknown. … August 1, 2017
Systematic Review Recommends Standard Ratios of Blood Products for Massive Transfusion Observational studies have suggested that higher ratios of plasma and platelets to red blood cells (RBCs) might lead to better… July 26, 2017
Intrinsic Platelet Reactivity does not Affect Transfusion Outcome Platelet reactivity to agonists has been shown to be different between donors yet consistent within the same individual. Researchers in… July 20, 2017
Reversal of Direct Oral Anticoagulants: a Systematic Review Direct oral anticoagulants (DOACs), such as dabigatran, rivaroxaban, apixaban, and edoxaban, have many advantages over warfarin for treating patients with… July 12, 2017
Gram-positive Bacterial Contamination of Platelets a Concern In a study recently published in TRANSFUSION, researchers from the Canadian Blood Services reported results from routine and quality control… July 6, 2017
