Behavior Modifications Support Changes to Restrictive RBC Transfusion Practices Accumulating evidence supports restrictive RBC transfusion practices, and guidelines such as those recently released by the AABB recommend transfusing when… June 27, 2018
Perioperative RBC Transfusions Linked to Increased Risk of Blood Clots Venous thromboembolism (VTE) is associated with 5-10% of all hospital deaths, or about 100,000 to 200,000 deaths each year in… June 20, 2018
Risk of Graft-Versus-Host Disease Dependent on Apheresis Device Used to Collect Allogeneic Stem Cells The composition of stem cell grafts can affect the risk of graft-versus-host disease (GvHD), time to engraftment, and relapse for… June 13, 2018
Transfusion Dependence for Leukemia Patients Shortens Hospice Stay Approximately 25,000 individuals in the United States die annually from leukemia. These individuals often require transfusions; however, hematologic oncologists have… June 6, 2018
Typing Blood Group Variants from Whole-Genome Sequencing Data Serological testing for ABO and RhD blood group compatibility has been standard practice for at least 60 years. ABO and… May 30, 2018
New Assessment Criteria to Diagnose and Manage Delayed Hemolytic Transfusion Reactions in Sickle Cell Patients Many patients with sickle cell disease (SCD) require chronic transfusions and are at risk for life-threatening delayed hemolytic transfusion reactions… May 23, 2018
WBC Alloimmunization Infrequent in Granulocyte Transfusions Neutropenia is characterized by abnormally low counts of neutrophils and is a common condition among patients receiving chemotherapy or hematopoietic… May 16, 2018
Revisiting Zika virus screening for donated blood In 2015, the Zika virus (ZIKV) rapidly spread to the Americas and other countries, and four possible transfusion-transmission cases were… May 10, 2018
Universal Donor Red Blood Cells Can Be Genetically Engineered Using CRISPR Gene Editing Alloimmunization commonly affects 2-5% of all transfusion recipients and approximately 30% of chronically transfused patients with sickle-cell disease. Since ABO… May 2, 2018
Gene Therapy for β-Thalassemia Patients who Are Transfusion Dependent β-thalassemia is one of the most common genetic diseases—especially in North Africa, the Middle East and Asia. About 60-80% of… April 25, 2018
