T cell Mediated Platelet Refractoriness Patients who are refractory to platelet transfusion are a challenge for transfusion services. Platelet refractoriness has historically been attributed to… April 13, 2016
Recombinant Thrombomodulin for Treatment of Transplant-Associated Thrombotic Microangiopathy Thrombotic microangiopathy (TMA) encompasses several overlapping clinical syndromes with different etiologies, based on a common pathologic lesion; TMA symptoms include… April 7, 2016
Zika Epidemic in Americas Began with Single Introduction in 2013 The Zika virus is a single stranded RNA virus of the Flaviviridae family transmitted primary by Aedes mosquitoes, although other… March 30, 2016
Cryopreserved Platelets are Hemostatically Functional in Vitro Inventory and storage of cryopreserved platelets (CPP) would be simple in comparison to platelets that are normally stored at room… March 23, 2016
Fresh Red Blood Cells May Be Associated with Mortality Depending on How They Are Processed Before Transfusion Several recent trials have determined that transfusion of older red blood cells (RBC) are not associated with adverse outcomes. However,… March 16, 2016
Severe Anemia Is Associated with Necrotizing Enterocolitis, not RBC Transfusions Necrotizing enterocolitis is the leading cause of mortality in preterm infants. Although there is conflicting evidence, red blood cell (RBC)… March 9, 2016
Eculizumab Treatment May Be Beneficial For Treating Hemolysis Transfusion Reactions in Patients with Sickle Cell Disease Delayed hemolytic transfusion reactions (DHTR) in patients with sickle cell disease can lead to multiple organ failure and may be… March 2, 2016
Acid-Treated Platelets May Be an Alternative to HLA-Matched Platelets for Transfusions HLA antibodies can lead to patients becoming refractory to platelet transfusions, and transfusions can be difficult when HLA-matched donors cannot… February 24, 2016
RBC Transfusions Are Best for Anemic Patients with Breast Cancer Many breast cancer patients are anemic due to either their treatment or disease. Researchers examined whether erythropoietin-stimulating agents such as… February 17, 2016
Blood from Younger Donors Does Not Affect Patient Survival after Transfusion Animal studies suggest blood from young donors may have rejuvenating effects for older patients. In a matched cohort study, researchers… February 10, 2016