Global Blood Supply Challenges The World Health Organization (WHO) considers blood an essential medicine, yet nearly two-thirds of countries—primarily low- and middle-income countries (LMIC)—lack… September 11, 2024
Prevalence and Trends of Maternal RBC Alloimmunization in the U.S. Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic… September 4, 2024
Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients Undergoing Liver Resection Tranexamic acid is a synthetic compound that prevents fibrin clot degradation and has been shown to reduce blood loss and… August 27, 2024
Blood Donation Rates Higher in Countries with Higher Healthcare Quality and Expenditure Most studies on blood donation rates have focused on individual donor behaviors, and little is known about how the quality… August 21, 2024
Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules… August 14, 2024
Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous… August 7, 2024
Updated FDA Guidance for Blood Donor Eligibility for Blood Pressure and Pulse The U.S. Food and Drug Administration (FDA) has previously provided guidance for the eligibility of blood donors with blood pressure… July 30, 2024
Carnitine Metabolism Associated with Red Blood Cell Hemolysis Red blood cells can be stored up to 42 days, after which they progressively develop a series of storage lesions—partly… July 25, 2024
No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized… July 17, 2024
RBC Transfusions Guidelines for Very Preterm Infants Most clinical practice guidelines for blood transfusion have focused on adults and limited recommendations are available for children and neonates…. July 9, 2024
