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Platelet Transfusion

Secondary Bacterial Culture for Platelets Reduces Transfusion Risk and Complies with FDA Draft Guidance for Platelet Safety

Platelets are most susceptible to bacterial contamination due to their storage conditions. In order to decrease the risk of bacterial…

April 4, 2018

Clinical Guidelines for Platelet Transfusions in Patients with Cancer

The American Society of Clinical Oncology (ASCO) has updated the clinical guidelines for platelet transfusions in patients with cancer. ASCO…

December 13, 2017

Cold-Storage for Platelets

Platelets are normally transfused either prophylactically for oncology and hematology patients, or to help stop severe bleeding. Since the mid-1980s,…

December 6, 2017

Cost Effectiveness of Platelets Treated with Pathogen Reduction Compared to Secondary Testing

In March of 2016 the FDA introduced draft guidelines recommending additional precautions to prevent bacterial contamination in platelets. Since both…

October 4, 2017

Low Hematocrit and Bleeding Risk for Patients with Hypoproliferative Thrombocytopenia

Prophylactic platelet transfusions are the standard of care for hypoproliferative thrombocytopenia. Over one thousand adult patients (n=1077) enrolled in a…

September 13, 2017

Leukoreduction of Platelet Units Followed by Mirasol Pathogen Reduction May Prevent Alloimmunization

Alloimmunization to donor platelets is common in transfused, immunosuppressed oncology patients. Leukoreduction reduces alloimmunization by more than half. Researchers recently…

August 30, 2017

Gram-positive Bacterial Contamination of Platelets a Concern

In a study recently published in TRANSFUSION, researchers from the Canadian Blood Services reported results from routine and quality control…

July 6, 2017

Higher Hematocrit Levels Are Associated with Increased Thrombosis Risk and Reduced Bleeding

A growing number of recent studies have observed an association between elevated hematocrit levels and thrombosis. However, the mechanism behind…

May 10, 2017

Prophylactic Platelet Transfusions are Not Superior to Supportive Care for Dengue Patients with Thrombocytopenia

According to the World Health Organization, the incidence of dengue has increased 30-fold in the past 50 years, and over…

April 12, 2017

Current Evidence Suggests that Non-invasive Procedures are Best to Treat Fetal and Neonatal Alloimmune Thrombocytopenia

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) occurs when maternal alloantibodies develop against fetal platelet antigens.  FNAIT may cause severe bleeding…

April 5, 2017

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  • Plasma Equivalent to Clotting Factor Concentrates for Initial Resuscitation of Patients with Severe Trauma

  • Personalized Prediction Model of Prophylactic Platelet Transfusions for Preterm Infants

  • Caffeine in Donor Blood Reduces Quality of Stored RBCs

  • Ferritin Levels Needed to Assess Hemoglobin Recovery after Blood Donation

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