Phosphatidylserine and Phosphatidylethanolamine Levels on RBCs Important for Transfusion Outcomes Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are phospholipids that normally reside in the inner leaflet of the red blood cell membrane…. December 10, 2025
Liberal or Restrictive Transfusion Thresholds for Surgery Patients with High Cardiac Risk Current RBC transfusion guidelines recommend a restrictive transfusion strategy for most patients, but ambiguity still remains for patients with high… November 12, 2025
RBC Transfusions in Neonatal ICUs Above Restrictive Hb Thresholds In 2020, two randomized clinical trials found that liberal RBC transfusion hemoglobin (Hb) thresholds were non-superior to restrictive thresholds for… October 23, 2025
Caffeine in Donor Blood Reduces Quality of Stored RBCs Caffeine, one of the most consumed psychoactive substances worldwide, is a non-selective antagonist of adenosine receptors, including ADORA2B expressed on… September 16, 2025
Transfusion of RBCs from Cord Blood May Protect Low-Weight Preterm Infants from Severe Retinopathy RBC transfusions in low-weight preterm infants are associated with retinopathy of prematurity (ROP), a visual impairment that affects their quality… September 4, 2025
AABB Guidelines Recommend Liberal RBC Transfusion for Patients with Acute Myocardial Infarction Restrictive transfusion hemoglobin (Hb) thresholds are currently recommended across multiple medical and surgical settings, but the optimal RBC transfusion threshold… August 27, 2025
Machine Learning Model for Estimating Perioperative Transfusion Risks Approximately 20% of RBC units are used for surgeries. Currently, hospitals estimate the risk of perioperative transfusions using historical charts… July 29, 2025
Blood Transfusion Strategies for Major Trauma Early transfusion is associated with reduced morbidity and mortality in major bleeding trauma events. However, the optimal mix of blood… July 22, 2025
Storage Duration Affects Hematological and Metabolic Parameters in Patients with Sickle Cell Disease Red blood cells (RBCs) may be stored for up to 42 days before transfusion; however, over time they may develop… July 16, 2025
RBCs with Reduced Deformability are Removed from Circulation RBCs, with a diameter of 8 µm, must squeeze through narrow microvascular spaces and endothelial clefts just 1 to 2.5… July 2, 2025
RBC Transfusion