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RBC Transfusion

Blood Transfusion Strategies for Major Trauma

Early transfusion is associated with reduced morbidity and mortality in major bleeding trauma events. However, the optimal mix of blood…

July 22, 2025

Storage Duration Affects Hematological and Metabolic Parameters in Patients with Sickle Cell Disease

Red blood cells (RBCs) may be stored for up to 42 days before transfusion; however, over time they may develop…

July 16, 2025

RBCs with Reduced Deformability are Removed from Circulation

RBCs, with a diameter of 8 µm, must squeeze through narrow microvascular spaces and endothelial clefts just 1 to 2.5…

July 2, 2025

Acute Normovolemic Hemodilution Does Not Reduce RBC Transfusions

Globally, over two million individuals undergo cardiac surgery annually, and about one third receive at least one unit of allogeneic…

June 18, 2025

Anemia Treatment Bundle Improves Hemoglobin Recovery after Critical Illness

Very few studies have examined how anemia management strategies affect post-hospitalization outcomes for critically ill patients. A recent randomized controlled…

April 16, 2025

Blood Collection and Transfusions Stable in the U.S.

According to the 2023 U.S. National Blood Collection and Utilization Survey (NBCUS), blood transfusions have stabilized following a sharp decline…

March 26, 2025

Sovleplenib to Treat Warm Autoimmune Hemolytic Anemia

Warm autoimmune hemolytic anemia is a rare and serious disorder with limited treatment options; RBC transfusions can provide short term…

March 12, 2025

Donor Age, Not Donor Sex, Is the Primary Factor Influencing RBC Deformability

RBC deformability—the ability to alter shape and squeeze through capillaries and other microvascular tissues—is essential for oxygen delivery to tissues…

March 5, 2025

Using Machine Learning Models to Predict the Likelihood of a Transfusion

Over 85 million units of RBCs are transfused annually worldwide, and the decision to transfuse is usually based on a…

February 26, 2025

Antibodies to Amustaline/Glutathione Pathogen Reduced RBCs

While the U.S. FDA has approved the use of pathogen reduction (PR) technologies for platelets and plasma, it has not…

February 12, 2025

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  • Blood Transfusion Strategies for Major Trauma

  • Storage Duration Affects Hematological and Metabolic Parameters in Patients with Sickle Cell Disease

  • Syphilis Infections Among US Blood Donors

  • RBCs with Reduced Deformability are Removed from Circulation

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