Sovleplenib to Treat Warm Autoimmune Hemolytic Anemia Warm autoimmune hemolytic anemia is a rare and serious disorder with limited treatment options; RBC transfusions can provide short term… March 12, 2025
Donor Age, Not Donor Sex, Is the Primary Factor Influencing RBC Deformability RBC deformability—the ability to alter shape and squeeze through capillaries and other microvascular tissues—is essential for oxygen delivery to tissues… March 5, 2025
Using Machine Learning Models to Predict the Likelihood of a Transfusion Over 85 million units of RBCs are transfused annually worldwide, and the decision to transfuse is usually based on a… February 26, 2025
Antibodies to Amustaline/Glutathione Pathogen Reduced RBCs While the U.S. FDA has approved the use of pathogen reduction (PR) technologies for platelets and plasma, it has not… February 12, 2025
A New, Simple Proxy to Measure Oxygen Unloading and the Quality of Stored Blood The functional quality of transfused blood depends upon oxygen delivery to the tissues. Oxygen carrying capacity is easily and routinely… January 16, 2025
Hypovolemic Phlebotomy Reduces Transfusions During Liver Surgery About 15% to 20% of patients undergoing liver resections require RBC transfusions. Current guidelines propose a number of options to… January 8, 2025
Liberal versus Restrictive Transfusion Thresholds for Patients with Subarachnoid Hemorrhage Aneurysmal subarachnoid hemorrhages may result in severe neurological problems with fatality rates reaching as high as 67%, particularly in patients… December 17, 2024
Blood Cell Salvage Decreases Transfusions After Decannulation from Extracorporeal Membrane Oxygenation (ECMO) Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supportive therapy improves outcomes and reduces mortality for patients with acute respiratory distress syndrome. VV-ECMO,… December 10, 2024
Multi-Country Review of ABO-Incompatible Red Blood Cell Transfusions Safety measures to prevent ABO-incompatible red blood cell (RBC) transfusions are in place throughout the entire process from blood donation… November 26, 2024
Wide Variations in Treatments and Outcomes Globally in Hemolytic Disease of the Fetus and Newborn Hemolytic disease of the fetus and newborn (HDFN) is a life-threatening disorder in which maternal alloantibodies destroy fetal and neonatal… November 19, 2024
RBC Transfusion