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RBC Transfusion

Liberal versus Restrictive Transfusion Thresholds for Patients with Subarachnoid Hemorrhage

Aneurysmal subarachnoid hemorrhages may result in severe neurological problems with fatality rates reaching as high as 67%, particularly in patients…

December 17, 2024

Blood Cell Salvage Decreases Transfusions After Decannulation from Extracorporeal Membrane Oxygenation (ECMO)

Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supportive therapy improves outcomes and reduces mortality for patients with acute respiratory distress syndrome. VV-ECMO,…

December 10, 2024

Multi-Country Review of ABO-Incompatible Red Blood Cell Transfusions

Safety measures to prevent ABO-incompatible red blood cell (RBC) transfusions are in place throughout the entire process from blood donation…

November 26, 2024

Wide Variations in Treatments and Outcomes Globally in Hemolytic Disease of the Fetus and Newborn

Hemolytic disease of the fetus and newborn (HDFN) is a life-threatening disorder in which maternal alloantibodies destroy fetal and neonatal…

November 19, 2024

RHD Genotyping May Enable D-positive RBC Units to be Transfused to Patients with Anti-D

Patients with sickle cell disease (SCD) often require chronic red blood cell exchanges. The American Society for Hematology recommends matching…

November 13, 2024

Intravenous vs Oral Iron for Pregnant Women in Africa

Worldwide, almost 40% of all pregnant women are anemic (hemoglobin < 11 g/dL) with the percentage rising to around 50%…

November 7, 2024

Liberal Transfusion Thresholds for Patients with Acute Brain Injury

Over the past 25 years, >45 randomized clinical trials have shown that a restrictive transfusion strategy is best for most…

October 17, 2024

RBCs Regulate Hemostasis Through Platelet-Dependent and -Independent Mechanisms

Red blood cells (RBCs) deliver oxygen to tissues and also contribute to hemostasis and thrombosis through platelet interactions that promote…

October 9, 2024

Liberal Transfusion Threshold of 9-10 g/dL for Patients with Myocardial Infarction

While restrictive transfusion hemoglobin (Hb) thresholds are appropriate for most patients, those with anemia and myocardial infarction (MI) may benefit…

October 2, 2024

Prevalence and Trends of Maternal RBC Alloimmunization in the U.S.

Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic…

September 4, 2024

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  • RBCs with Reduced Deformability are Removed from Circulation

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  • Acute Normovolemic Hemodilution Does Not Reduce RBC Transfusions

  • Blood Donation Teams—a Novel Strategy to Support Novice Donors

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