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RBC Transfusion

Luspatercept Reduces Transfusion-Dependence for Anemic Patients with Myelofibrosis

Myelofibrosis is a rare bone marrow cancer characterized by excessive scarring that disrupts the production of red blood cells. Current…

June 11, 2024

Study Finds No Association Between RBC Transfusions and Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) affects approximately 1 in 1000 premature babies, usually two to six weeks after birth, and accounts for…

May 7, 2024

Gut Microbe Exoglycosidases Target ABO Blood Group Antigens to Generate ABO-Universal Blood

The ABO blood group is the most immunogenic group of blood antigens, and incompatible mismatched ABO-blood is among the most…

May 1, 2024

Transfusion Patterns After CAR T-Cell Therapy for Large B-Cell Lymphoma

Three different types of chimeric antigen receptor (CAR) T-cell therapies have been approved to treat refractory or relapsed large B-cell…

April 10, 2024

Stored RBCs May Have Slower Oxygen Unloading for Tissue

Oxygen delivery to tissues is dependent on blood flow, the oxygen carrying capacity of the RBCs (related to hemoglobin levels),…

March 27, 2024

Recombinant Erythropoietin for Patients with Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AIHA) is a rare disorder with multiple etiologies and usually presents as anemia with hemolysis. Initial treatments…

March 21, 2024

Strategies for Blood Deserts

Every country in sub-Saharan Africa and South Asia, along with some other low-income and middle-income countries often experience blood shortages….

February 28, 2024

Low Alloimmunization Risk if No Antibodies Formed during First 20 RBC Transfused Units

RBC transfusions are critical for many patients with sickle cell disease.  Patients are at risk, however, of developing alloantibodies, which…

January 4, 2024

Thalidomide Reduces Bleeding and Blood Transfusions in Patients with Small-Intestinal Angiodysplasia

Small-intestinal angiodysplasia (SIA), characterized by vascular malformation in the GI tract, is the most common cause of recurrent bleeding in…

December 27, 2023

Darbepoetin Alfa Reduces RBC Transfusions in Infants with HDFN Treated with Intrauterine Transfusions

Hemolytic disease of the fetus and newborn (HDFN) is a severe disorder caused by maternal antibodies against fetal RBC antigens…

December 6, 2023

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  • AABB Guidelines Recommend Liberal RBC Transfusion for Patients with Acute Myocardial Infarction

  • Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens

  • Transfusion-related Alpha-Gal Syndrome

  • 2024 Serious Hazards of Transfusions (SHOT) Report in the U.K.

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