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RBC Transfusion

Increased Blood Use and Cost for Emergency Transfusions with Whole Blood Compared to Packed Red Blood Cells

In the past two decades, a growing number of hospitals have started using whole blood to treat trauma patients and…

February 16, 2023

Thromboelastometry and Clinical Guidance for Fibrinogen Infusions during Liver Transplantation

Thromboelastometry provides individualized measures of clot kinetics and structure, and has played an increasingly important role in the management of…

February 8, 2023

Sickle Cell Trait Testing of RBC Units

While individuals with the sickle cell trait (SCT) have a single allele of hemoglobin S (HbS) and are eligible blood…

December 27, 2022

Hypoxic Storage Helps to Preserve Red Blood Cells

Red blood cells (RBCs) may be stored for up to 42 days, but over time storage lesions also develop.  These…

November 22, 2022

Transfusion Thresholds for Patients Receiving ECMO

Venovenous extracorporeal membrane oxygenation (ECMO) can be used to help provide respiratory support to patients with severe acute respiratory distress…

November 2, 2022

Sex-Matched Transfusions May Reduce Mortality

While plasma from female donors increases the risk of transfusion-related acute lung injury (TRALI), observational studies have had conflicting results…

October 6, 2022

Mitapivat Trial Results in Adults with Pyruvate Kinase Deficiency Requiring Transfusions

Pyruvate kinase deficiency is a rare, congenital form of chronic hemolytic anemia.  Current treatments for pyruvate kinase deficiency, including RBC…

August 31, 2022

Results from Phase 1 Trial for Artificial Hemoglobin Vesicles

Advantages of artificial red blood cells (RBCs) include reduced risks of pathogens and alloimmunization and greater storage time compared to…

August 24, 2022

Safety and Effectiveness of Tranexamic Acid in Cardiac Surgery Patients

Tranexamic acid is an antifibrinolytic agent that is commonly used to control bleeding in patients undergoing cardiac surgery.  Limited randomized…

August 10, 2022

Racial Differences in Red Blood Cell Transfusions

Transfusion guidelines recommend transfusing red blood cells (RBCs) when hemoglobin (Hb) levels drop below 7 or 8 g/dL, but variation…

August 3, 2022

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