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Serology/Genotyping

Dithiothreitol (DTT)-based Method Validated for Blood Compatibility Testing in Patients Taking Daratumumab

Daratumumab (DARA), an immunoglobulin that targets CD38 on myeloma cells, was recently approved by the U.S. FDA. DARA, however, also…

September 14, 2016

Combinations of Monoclonal Antibodies Efficiently Suppress Red Blood Cell Alloimmunization in Mice

Polyclonal anti-RhD antibodies are used to prevent hemolytic disease of the fetus and newborn. These antibodies are currently collected from…

August 31, 2016

Mass-Scale Red Blood Cell Genotyping May Assist in Finding Antigen Negative Blood

Finding antigen negative blood is difficult and time consuming, especially when using serologic methods. The Blood Center of Wisconsin recently…

October 23, 2015

VIDEO: RHD genotyping for obstetric patients with a serologic weak D phenotype

Today we will be discussing patients that have a weak D phenotype for their Rh blood group antigen. Since the…

September 15, 2015

Enzymatic Removal of A- and B-Blood Group Antigenic Determinants To Generate Universal Blood May Be Feasible

Matching ABO antigens for RBC transfusions is time consuming and limits inventory. Research now shows how this barrier could be…

May 8, 2015

AB Blood Group is Associated with Cognitive Impairment

In a recent case-controlled study published in Neurology, researchers assessed the relationship between ABO blood group, factor VIII, and the…

September 26, 2014

VIDEO: Vel Established as New Blood Group System

Researchers have identified the molecular basis of the Vel antigen. This work establishes the gene encoding the small integral membrane protein…

May 30, 2013

VIDEO: Red Cell Alloimmunization

Two studies and an editorial published in the journal Transfusion discuss red cell alloimmunization among patients with sickle cell disease…

April 15, 2013

New Histo-Blood Group System Defined in Humans

For the first time, researchers have provided conclusive evidence to support the definition of FORS, a new histo-blood group system…

March 8, 2013

Matrix-Assisted Laser Deabsorption/Ionization Time of Flight Mass Spectrometry Shows Promise for Blood Group Genotyping

A collaborative project between researchers in Switzerland and Germany suggests that matrix-assisted laser deabsorption/ionization time of flight mass spectrometry (MALDI-TOF…

December 21, 2012

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