The Genealogy of Blood Cells Hematopoietic stem cells (HSCs) give rise to all types of blood cells through myeloid progenitor cell types (e.g., red blood… January 31, 2024
High-Dose Cryoprecipitate for Hemorrhage after Trauma Worldwide, hemorrhage contributes to at least half of the 4.4 million trauma deaths annually. Recent studies have found that either… October 25, 2023
Induced Abortion Does Not Increase Rh Alloimmunization Rh immunoglobulin routinely given to Rh-negative pregnant women during the second and third trimesters has reduced the maternal Rh sensitization… October 4, 2023
Limited Data for Plasmapheresis to Treat Post-COVID-19 Condition The COVID-19 pandemic has caused substantial morbidity and mortality. One study estimates that close to 13% of infected individuals experience… August 30, 2023
Consensus Definition for Massive Transfusion? Severe bleeding is commonly encountered in surgery, trauma, gastrointestinal hemorrhage and obstetrics and may require massive transfusion (MT). A universal… July 20, 2023
Luspatercept versus Epoetin Alfa for Lower-Risk Myelodysplastic Syndrome Myelodysplastic syndromes (MDS) are caused by a heterogeneous group of hematopoietic stem cell disorders and can progress to acute myeloid… July 12, 2023
Long-term Survival of Severe Trauma Patients Treated with Tranexamic Acid Globally, trauma is the leading cause of death for young people. In 2011, the World Health Organization added tranexamic acid… June 21, 2023
Trauma Endotypes and Transfusion Resuscitation Strategies In 2015 results from the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial suggested that a 1:1:1 ratio of… May 24, 2023
Prothrombin Complex Concentrate Increases Risk of Thromboembolic Events in Trauma Patients Four-factor prothrombin complex concentrate (4F-PCC) is a lyophilized concentrate of coagulation factors that is commonly used for urgent reversal of… March 29, 2023
Acute Normovolemic Hemodilution Reduces Transfusions in Patients Undergoing Cardiac Surgery Approximately one to two million cardiac surgery operations are performed worldwide each year accounting for about 80% of all surgical… March 15, 2023
Special Transfusion Situations