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Archives for January–April 2017

Transfusion of Red Blood Cells from Younger Donors Is Not Associated with Improved Survival

Animal models suggest that blood from younger donors may provide revitalizing benefits, but findings from observational cohort studies on this…

April 26, 2017

Stored Whole Blood Treated with Pathogen Reduction Acceptable for Transfusion

Pathogen reduction technology (PRT) hold promise for eliminating many known and emerging pathogens in donated blood and thus preventing transfusion…

April 19, 2017

Prophylactic Platelet Transfusions are Not Superior to Supportive Care for Dengue Patients with Thrombocytopenia

According to the World Health Organization, the incidence of dengue has increased 30-fold in the past 50 years, and over…

April 12, 2017

Current Evidence Suggests that Non-invasive Procedures are Best to Treat Fetal and Neonatal Alloimmune Thrombocytopenia

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) occurs when maternal alloantibodies develop against fetal platelet antigens.  FNAIT may cause severe bleeding…

April 5, 2017

Large-Scale Iron Testing Feasible for Blood Centers

Iron deficiency is a common problem among frequent blood donors. The Canadian Blood Services recently sought to identify donors at…

March 29, 2017

Survival for Non-Trauma Patients Transfused with High Ratios of Plasma to Red Blood Cells

Although numerous studies have reported improved survival for trauma patients transfused with higher ratios of fresh frozen plasma (FFP) compared…

March 22, 2017

Liquid Plasma Acceptable for Severe Trauma Patients with Major Bleeding

Recent studies have highlighted the importance of expeditious transfusion of plasma, platelets and red blood cells in a 1:1:1 ratio…

March 16, 2017

New PLASMIC Scoring System to Help Diagnose Thrombotic Thrombocytopenic Purpura

Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder caused by a lack of ADAMTS13 activity, which normally cleaves the…

March 8, 2017

Administration of Fibrinogen Concentrate during Cardiac Surgery Does Not Significantly Reduce Blood Loss

Since fibrinogen plays a key role in hemostasis and it is rapidly depleted during cardiac surgery, many cardiac surgeons give…

March 1, 2017

Patients with Hematologic Cancers Have Lower Rates of Alloimmunization with RhD

Over 20% of RhD-negative non-oncology patients exposed to RhD-positive red blood cells (RBCs) become alloimmunized to the RhD antigen. In…

February 22, 2017

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