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Archives for May–August 2025

AABB Guidelines Recommend Liberal RBC Transfusion for Patients with Acute Myocardial Infarction

Restrictive transfusion hemoglobin (Hb) thresholds are currently recommended across multiple medical and surgical settings, but the optimal RBC transfusion threshold…

August 27, 2025

Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens

Of the approximately 400 RBC blood group antigens, only ABO/D are matched for routine transfusions. Some RBC blood group antigens…

August 20, 2025

Transfusion-related Alpha-Gal Syndrome

Alpha-gal syndrome (AGS), first described in 2009, is associated with a tick bite in which exposed individuals develop IgE antibodies…

August 13, 2025

2024 Serious Hazards of Transfusions (SHOT) Report in the U.K.

The Royal College of Pathologists in the United Kingdom recently published their annual report for 2024 on the Serious Hazards…

August 6, 2025

Machine Learning Model for Estimating Perioperative Transfusion Risks

Approximately 20% of RBC units are used for surgeries. Currently, hospitals estimate the risk of perioperative transfusions using historical charts…

July 29, 2025

Blood Transfusion Strategies for Major Trauma

Early transfusion is associated with reduced morbidity and mortality in major bleeding trauma events. However, the optimal mix of blood…

July 22, 2025

Storage Duration Affects Hematological and Metabolic Parameters in Patients with Sickle Cell Disease

Red blood cells (RBCs) may be stored for up to 42 days before transfusion; however, over time they may develop…

July 16, 2025

Syphilis Infections Among US Blood Donors

Syphilis is a sexually transmitted bacterial infection that may also be transmitted by transfusion.  Active cases of syphilis are increasing…

July 10, 2025

RBCs with Reduced Deformability are Removed from Circulation

RBCs, with a diameter of 8 µm, must squeeze through narrow microvascular spaces and endothelial clefts just 1 to 2.5…

July 2, 2025

Array-based, comprehensive genotyping for erythroid, platelet, neutrophil and leukocyte antigens

Alloimmunization occurs in about 2-5% of transfused patients, even when ABO and RhD blood groups are matched, and rates are…

June 26, 2025

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Latest News

  • Transfusion of RBCs from Cord Blood May Protect Low-Weight Preterm Infants from Severe Retinopathy

  • AABB Guidelines Recommend Liberal RBC Transfusion for Patients with Acute Myocardial Infarction

  • Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens

  • Transfusion-related Alpha-Gal Syndrome

    Question of the Day

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