Cryopreserved vs. Standard Platelets for Surgical Bleeding Hospitals in low- and middle-income countries, as well as military and rural hospitals in high-income countries, lack reliable access to… December 17, 2025
Phosphatidylserine and Phosphatidylethanolamine Levels on RBCs Important for Transfusion Outcomes Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are phospholipids that normally reside in the inner leaflet of the red blood cell membrane…. December 10, 2025
Blood Donation and Improved Cardiometabolic Health Excess stored iron can lead to health complications including insulin resistance and cardiometabolic problems. Excess stored iron may also be… December 2, 2025
Mitochondrial DNA Acts as a “First Hit” for Antibody-Mediated TRALI Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality, but its pathogenesis is complex and not well… November 20, 2025
Liberal or Restrictive Transfusion Thresholds for Surgery Patients with High Cardiac Risk Current RBC transfusion guidelines recommend a restrictive transfusion strategy for most patients, but ambiguity still remains for patients with high… November 12, 2025
Iron Supplementation for Blood Donors Based on Ferritin Levels With each whole blood donation, donors lose approximately 250 mg of iron and have a higher risk of developing iron… November 5, 2025
Impact of Individual Donor Assessment Deferral Changes on Donor HIV, HBV, HCV, and Syphilis Prevalence In 2023, the U.S. Food and Drug Administration (FDA) guidelines for blood donations shifted from a 3-month deferral for donors… October 29, 2025
RBC Transfusions in Neonatal ICUs Above Restrictive Hb Thresholds In 2020, two randomized clinical trials found that liberal RBC transfusion hemoglobin (Hb) thresholds were non-superior to restrictive thresholds for… October 23, 2025
Locally Transmitted Malaria in the United States Currently, half of the world’s population is at risk for malaria. Although malaria was endemic across the southern region of… October 15, 2025
Global Platelet Transfusion Practices for Patients in the ICU Platelet transfusion rates for patients in the ICU range from 5% to 15%, but guidelines are primarily based on observational… October 8, 2025
