Clinical Guidelines for Anemia and Chronic Kidney Disease The Kidney Disease: Improving Global Outcomes (KDIGO) committee has updated their 2012 guidelines for the management of anemia in patients… January 28, 2026
Ferritin-Guided Donation Policies Decrease Iron Deficiency Most blood establishments monitor hemoglobin (Hb) levels to prevent anemia, but Hb monitoring does not protect against iron deficiency (ID)…. January 14, 2026
RBC Transfusions to Treat Acute Heavy Menstrual Bleeding About one in four women of reproductive age experience uncomfortable and painful heavy menstrual bleeding. For some women, the pain… January 7, 2026
RBC Transfusion Outcomes Similar in ICU Patients with and Without Cardiovascular Disease In intensive care units (ICU), 25%-50% of patients receive RBC transfusions. Up to 30-40% of ICU patients also have a… January 7, 2026
Cryopreserved vs. Standard Platelets for Surgical Bleeding Hospitals in low- and middle-income countries, as well as military and rural hospitals in high-income countries, lack reliable access to… December 17, 2025
Phosphatidylserine and Phosphatidylethanolamine Levels on RBCs Important for Transfusion Outcomes Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are phospholipids that normally reside in the inner leaflet of the red blood cell membrane…. December 10, 2025
Blood Donation and Improved Cardiometabolic Health Excess stored iron can lead to health complications including insulin resistance and cardiometabolic problems. Excess stored iron may also be… December 2, 2025
Mitochondrial DNA Acts as a “First Hit” for Antibody-Mediated TRALI Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality, but its pathogenesis is complex and not well… November 20, 2025
Liberal or Restrictive Transfusion Thresholds for Surgery Patients with High Cardiac Risk Current RBC transfusion guidelines recommend a restrictive transfusion strategy for most patients, but ambiguity still remains for patients with high… November 12, 2025
Iron Supplementation for Blood Donors Based on Ferritin Levels With each whole blood donation, donors lose approximately 250 mg of iron and have a higher risk of developing iron… November 5, 2025
