Matching RH Genotypes for Patients with Sickle Cell Disease RH antigens are encoded by two highly polymorphic genes, RHD and RHCE. Homologous recombination and novel polymorphism have resulted in… September 19, 2018
Restrictive Transfusion Strategy for Cardiac Surgery Patients Previous studies have reported that restrictive transfusion strategies are non-inferior compared to liberal strategies for cardiac surgery patients followed up… August 30, 2018
Perioperative RBC Transfusions Linked to Increased Risk of Blood Clots Venous thromboembolism (VTE) is associated with 5-10% of all hospital deaths, or about 100,000 to 200,000 deaths each year in… June 20, 2018
New Assessment Criteria to Diagnose and Manage Delayed Hemolytic Transfusion Reactions in Sickle Cell Patients Many patients with sickle cell disease (SCD) require chronic transfusions and are at risk for life-threatening delayed hemolytic transfusion reactions… May 23, 2018
Transfusion-Associated Circulatory Overload (TACO) Difficult to Diagnosis in Children Transfusion-associated circulatory overload (TACO) is currently one of the leading causes of transfusion-related deaths even though it is often underdiagnosed… March 28, 2018
Transfusion Patients with Hereditary Hemorrhagic Telangiectasia Have Increased Risk of Alloimmunization Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is an autosomal dominate disorder characterized by arteriovenous malformations. In patients… March 7, 2018
Alloimmunization to One RBC Antigen Triggers Alloimmunization to Other RBC Antigens The risk of alloimmunization to polymorphic RBC antigens is high for individuals who undergo chronic transfusion therapy. Researchers recently utilized… January 31, 2018
Restrictive Transfusions Threshold Safe for Cardiac Surgery Patients While a restrictive transfusion strategy has been advocated for most patients, a restrictive approach for cardiac surgery patients may put… November 22, 2017
Genetic Variation in the Fc-gamma Receptor Gene is Associated with Protection against RBC Alloimmunization Genetic variation in the Fc-ɣ receptor gene has been shown to be associated with some auto- and alloimmune diseases. Researchers… November 16, 2017
Trying to Decipher Relationship between Previously Pregnant Donors and RBC Transfusion-related Mortality Although blood from previously pregnant female donors has been shown to be associated with transfusion-related acute lung injury (TRALI), the… October 25, 2017
Adverse Events (non-infectious)