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Adverse Events (non-infectious)

Restrictive Transfusion Strategy for Cardiac Surgery Patients

Previous studies have reported that restrictive transfusion strategies are non-inferior compared to liberal strategies for cardiac surgery patients followed up…

August 30, 2018

Perioperative RBC Transfusions Linked to Increased Risk of Blood Clots

Venous thromboembolism (VTE) is associated with 5-10% of all hospital deaths, or about 100,000 to 200,000 deaths each year in…

June 20, 2018

New Assessment Criteria to Diagnose and Manage Delayed Hemolytic Transfusion Reactions in Sickle Cell Patients

Many patients with sickle cell disease (SCD) require chronic transfusions and are at risk for life-threatening delayed hemolytic transfusion reactions…

May 23, 2018

Transfusion-Associated Circulatory Overload (TACO) Difficult to Diagnosis in Children

Transfusion-associated circulatory overload (TACO) is currently one of the leading causes of transfusion-related deaths even though it is often underdiagnosed…

March 28, 2018

Transfusion Patients with Hereditary Hemorrhagic Telangiectasia Have Increased Risk of Alloimmunization

Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is an autosomal dominate disorder characterized by arteriovenous malformations. In patients…

March 7, 2018

Alloimmunization to One RBC Antigen Triggers Alloimmunization to Other RBC Antigens

The risk of alloimmunization to polymorphic RBC antigens is high for individuals who undergo chronic transfusion therapy.  Researchers recently utilized…

January 31, 2018

Restrictive Transfusions Threshold Safe for Cardiac Surgery Patients

While a restrictive transfusion strategy has been advocated for most patients, a restrictive approach for cardiac surgery patients may put…

November 22, 2017

Genetic Variation in the Fc-gamma Receptor Gene is Associated with Protection against RBC Alloimmunization

 Genetic variation in the Fc-ɣ receptor gene has been shown to be associated with some auto- and alloimmune diseases. Researchers…

November 16, 2017

Trying to Decipher Relationship between Previously Pregnant Donors and RBC Transfusion-related Mortality

Although blood from previously pregnant female donors has been shown to be associated with transfusion-related acute lung injury (TRALI), the…

October 25, 2017

Bedside Checklists Could Prevent Most ABO-Incompatible Transfusions and Other Adverse Events

Since 1996, the hemovigilance surveillance system in the United Kingdom has collected and published yearly reports on the serious hazards…

August 16, 2017

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  • Directed Blood Donations Should be Limited

  • Babesia Infection Reduces Red Cell Deformability

  • New Erythropoietin Gene Variants Linked to Hereditary Erythrocytosis

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