Potential Screening for Cytomegalovirus among Cord Blood Donors Infection with cytomegalovirus (CMV) can cause severe complications for hematopoietic stem cell transplant patients. In addition to screening for maternal… November 9, 2017
Patients with Moderate ADAMTS13 Deficiency have Increased Risk of Dying Thrombotic microangiopathies (TMAs) may develop from diverse group of etiologies. While activity levels less than 10% of ADAMTS13 help to… September 21, 2017
Negligible Risk of Transfusion-Transmitted Creutzfeldt Jakob Disease Creutzfeldt Jakob Disease (CJD) is a fatal and rapidly progressing neurodegenerative disorder caused by misfolded proteins, or prions, in the… August 10, 2017
Reversal of Direct Oral Anticoagulants: a Systematic Review Direct oral anticoagulants (DOACs), such as dabigatran, rivaroxaban, apixaban, and edoxaban, have many advantages over warfarin for treating patients with… July 12, 2017
Risk of Hepatitis E Virus Positive Blood Donations Low in Canada Hepatitis E virus (HEV) is endemic in many resource-limited settings. HEV infection is usually asymptomatic; however, it can cause severe… June 14, 2017
Apheresis Lymphocyte Collections for CAR-T Cell Production Usually Well Tolerated By Cancer Patients Production of chimeric antigen receptor (CAR) T-cells involve genetically modifying the patient’s own T-cells, and these cells have been shown… May 17, 2017
Large-Scale Iron Testing Feasible for Blood Centers Iron deficiency is a common problem among frequent blood donors. The Canadian Blood Services recently sought to identify donors at… March 29, 2017
Liquid Plasma Acceptable for Severe Trauma Patients with Major Bleeding Recent studies have highlighted the importance of expeditious transfusion of plasma, platelets and red blood cells in a 1:1:1 ratio… March 16, 2017
Improving Peripheral Blood Stem Cell Collection for Autologous Stem Cell Transplantation The City of Hope National Medical Center in California performs nearly 400 autologous stem cell transplants (ASCT) per year using… January 11, 2017
Laboratory Testing is Suggested Before Intravenous Immunoglobulin is Given to Neonates Although intravenous immunoglobulin (IVIG) use is documented to treat a wide range of severe disorders in adults, IVIG use in… November 9, 2016