Sex-Matched Transfusions May Reduce Mortality While plasma from female donors increases the risk of transfusion-related acute lung injury (TRALI), observational studies have had conflicting results… October 6, 2022
Iron Repletion Does Not Effect Donor Well-Being or Red Cell Quality Iron deficiency develops in over one third of regular, repeat blood donors. In order to exam the physiological consequences of… September 28, 2022
Prophylactic Tranexamic Acid Does Not Decrease Bleeding or Transfusions in Patients with Hematologic Malignancies Patients with hematologic malignancies account for 43% of the 2 million platelet doses transfused in the U.S. each year. Despite… September 21, 2022
Donor Deferral Recommendations for HIV Pre-exposure Prophylaxis In December 2021, the U.S. FDA approved injectable cabotegravir (Apretude) as pre-exposure prophylaxis (PrEP) to prevent HIV transmission. PrEP, post-exposure… September 14, 2022
SARS-CoV-2 RNA Frequently Found in Blood Donor Plasma is Not Infectious Although no cases of SARS-CoV-2 transfusion-transmission have been reported worldwide, RNA is detected in 15% to 90% of patients with… September 7, 2022
Mitapivat Trial Results in Adults with Pyruvate Kinase Deficiency Requiring Transfusions Pyruvate kinase deficiency is a rare, congenital form of chronic hemolytic anemia. Current treatments for pyruvate kinase deficiency, including RBC… August 31, 2022
Results from Phase 1 Trial for Artificial Hemoglobin Vesicles Advantages of artificial red blood cells (RBCs) include reduced risks of pathogens and alloimmunization and greater storage time compared to… August 24, 2022
U.S. FDA Advises Blood Community Regarding Monkeypox Virus The World Health Organization recently declared the current monkeypox epidemic a public health emergency. First identified in laboratory monkeys in… August 16, 2022
Safety and Effectiveness of Tranexamic Acid in Cardiac Surgery Patients Tranexamic acid is an antifibrinolytic agent that is commonly used to control bleeding in patients undergoing cardiac surgery. Limited randomized… August 10, 2022
Racial Differences in Red Blood Cell Transfusions Transfusion guidelines recommend transfusing red blood cells (RBCs) when hemoglobin (Hb) levels drop below 7 or 8 g/dL, but variation… August 3, 2022
