Variable Transfusion Practices for Bleeding ICU Patients Globally Approximately 40-50% of patients in the intensive care unit (ICU) receive blood transfusions. Many studies have focused on bleeding in… January 19, 2022
Plasma Exchange for Hypertriglyceridemic Acute Pancreatitis Acute pancreatitis can be caused by many etiologies including high levels of plasma triglycerides. Hypertriglyceridemic acute pancreatitis (HTGAP) can cause… January 11, 2022
LentiGlobin Therapy for Sickle Cell Disease Sickle cell disease (SCD) is caused by a single point mutation in the β-globin gene and affects around 100,000 people… January 4, 2022
Cost-Effectiveness of Transfusions to Prevent Silent Cerebral Infarcts in Children with Sickle Cell Disease Guidelines published by the American Society of Hematology in 2020 recommend annual transcranial doppler ultrasound (TCD) screening to help identify… December 29, 2021
Outpatient COVID-19 Convalescent Plasma Reduces Hospitalizations While more than 500,000 units of COVID-19 convalescent plasma (CCP) have been transfused in the United States alone, the use… December 21, 2021
Cold-Stored Group O Whole Blood Use in Severely Injured Patients Trauma patients have a severe risk of hemorrhagic shock, and managing their platelet count is crucial for their survival. In… December 14, 2021
FDA Update about Bacterial Contamination of Platelets The United Stated Food and Drug Administration (FDA) issued guidance to reduce the risk of septic transfusion reactions associated with… December 8, 2021
Daprodustat is Noninferior to Erythropoiesis-Stimulating Agents for Patients with Chronic Kidney Disease Undergoing Dialysis According to the U.S. CDC, about 37 million adults in the United States have chronic kidney disease (CKD). As CKD… December 1, 2021
X- and Gamma-Irradiation Impact Red Blood Cells Similarly Transfusion-associated graft versus host disease (TA-GVHD) is a rare complication that occurs when histoincompatible viable lymphocytes are transfused into an… November 22, 2021
Platelet-Rich Plasma Injections Do Not Improve Ankle Osteoarthritis Ankle (tibiotalar) osteoarthritis affects approximately 3.4% of adults and is associated with a reduced quality of life. Effective non-surgical treatments… November 17, 2021