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Archive by Topic » News

Are WHO Guidelines for Serum Ferritin Levels for Female Blood Donors Too Low?

The current World Health Organization (WHO) guidelines, based on expert opinion with low-grade evidence, define iron deficiency in healthy blood…

July 6, 2022

Educational Materials Help to Retain Donors after a Temporary Deferral

Previous studies have found that temporarily deferred donors sometimes believe that their deferral is permanent.  In order to determine whether…

June 29, 2022

Transfusion Guidelines for Major Hemorrhage

Major hemorrhage is an emergency with significant morbidity and mortality.  The British Society for Haematology (BSH) has updated transfusion guidelines…

June 22, 2022

Donor-Recipient Sex and RBC Transfusion Outcomes

Deferring plasma from multiparous females has dramatically reduced the incidence of antibody-mediated transfusion-related acute lung injury (TRALI).  Some observational studies…

June 14, 2022

Anti-CD19 CAR-T Cells as First-Line Therapy for High-Risk Large B-Cell Lymphoma

Large-B-cell lymphoma (LBCL) is one of the most common types of non-Hodgkin lymphoma, and many patients do not respond well…

June 7, 2022

Updated FDA Guidance to Reduce Risk of Transmission of Creutzfeldt-Jakob Disease

The U.S. Food and Drug Administration (FDA) has issued updated guidance to reduce the transfusion-related transmission risk of Creutzfeldt-Jakob disease…

June 1, 2022

Genomic Profiles Associated with CAR T-Cell Therapy Efficacy

Chimeric antigen receptor (CAR) T-cell therapy is a promising therapy used to treat hematological cancers by targeting a specific antigen. …

May 24, 2022

Risk Factors for Allergic Transfusion Reactions in Pediatric Patients

Allergic transfusion reactions (ATRs) are common and can range from mild to severe.  Younger age, hematological/oncological disease, increasing number of…

May 17, 2022

Target Trial Emulation Using Real World Data Suggest Older RBCs May Increase Mortality

Data from many randomized clinical trials (RCTs) have not found an impact of storage time of red blood cells on…

May 11, 2022

Tranexamic Acid in Noncardiac Surgeries

Large randomized clinical trials have shown that tranexamic acid safely reduces bleeding in patients undergoing cardiac surgery or cesarean sections,…

May 3, 2022

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