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Archive by Topic » News

Donor-Recipient Sex and RBC Transfusion Outcomes

Deferring plasma from multiparous females has dramatically reduced the incidence of antibody-mediated transfusion-related acute lung injury (TRALI).  Some observational studies…

June 14, 2022

Anti-CD19 CAR-T Cells as First-Line Therapy for High-Risk Large B-Cell Lymphoma

Large-B-cell lymphoma (LBCL) is one of the most common types of non-Hodgkin lymphoma, and many patients do not respond well…

June 7, 2022

Updated FDA Guidance to Reduce Risk of Transmission of Creutzfeldt-Jakob Disease

The U.S. Food and Drug Administration (FDA) has issued updated guidance to reduce the transfusion-related transmission risk of Creutzfeldt-Jakob disease…

June 1, 2022

Genomic Profiles Associated with CAR T-Cell Therapy Efficacy

Chimeric antigen receptor (CAR) T-cell therapy is a promising therapy used to treat hematological cancers by targeting a specific antigen. …

May 24, 2022

Risk Factors for Allergic Transfusion Reactions in Pediatric Patients

Allergic transfusion reactions (ATRs) are common and can range from mild to severe.  Younger age, hematological/oncological disease, increasing number of…

May 17, 2022

Target Trial Emulation Using Real World Data Suggest Older RBCs May Increase Mortality

Data from many randomized clinical trials (RCTs) have not found an impact of storage time of red blood cells on…

May 11, 2022

Tranexamic Acid in Noncardiac Surgeries

Large randomized clinical trials have shown that tranexamic acid safely reduces bleeding in patients undergoing cardiac surgery or cesarean sections,…

May 3, 2022

Perfluoroalkyl and Polyfluoroalkyl Levels after Blood Donations

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are ubiquitous synthetic compounds found in many products, including Teflon, water-resistant materials, paints, and firefighting…

April 27, 2022

Guidelines for Hemolytic Disease of the Newborn

Hemolytic disease of the newborn (HDN) is a serious disease associated with significant morbidity and mortality.   HDN occurs when maternal…

April 20, 2022

AABB Issues COVID-19 Convalescent Plasma Clinical Practice Guidelines

The use of COVID-19 convalescent plasma (CCP) has been highly controversial since the beginning of the pandemic.  With the Food…

April 12, 2022

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