Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous… August 7, 2024
Updated FDA Guidance for Blood Donor Eligibility for Blood Pressure and Pulse The U.S. Food and Drug Administration (FDA) has previously provided guidance for the eligibility of blood donors with blood pressure… July 30, 2024
Carnitine Metabolism Associated with Red Blood Cell Hemolysis Red blood cells can be stored up to 42 days, after which they progressively develop a series of storage lesions—partly… July 25, 2024
No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized… July 17, 2024
RBC Transfusions Guidelines for Very Preterm Infants Most clinical practice guidelines for blood transfusion have focused on adults and limited recommendations are available for children and neonates…. July 9, 2024
Ferritin-Guided Blood Donations Protect Iron Stores in Donors In both North America and Europe, whole blood donors are eligible to donate whole blood every 56 days. Donors lose… July 3, 2024
Donor Deferral Model Evaluates Impact of New Individual Risk Assessment When AIDS emerged in the early 1980s, the risk of acquiring HIV from a transfusion was approximately 1.1%. The U.S…. June 28, 2024
Liberal versus Restrictive Transfusion Strategy for Patients with Traumatic Brain Injury and Anemia While a restrictive RBC transfusion strategy has been shown to be safe and effective for most patients, there is uncertainty… June 19, 2024
Luspatercept Reduces Transfusion-Dependence for Anemic Patients with Myelofibrosis Myelofibrosis is a rare bone marrow cancer characterized by excessive scarring that disrupts the production of red blood cells. Current… June 11, 2024
FDA: Donor Screening of Zika Virus Unnecessary in United States In 2015 and 2016, large outbreaks of the mosquito-borne Zika virus occurred in the Americas. Infection with the Zika virus… June 5, 2024