Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens Of the approximately 400 RBC blood group antigens, only ABO/D are matched for routine transfusions. Some RBC blood group antigens… August 20, 2025
Transfusion-related Alpha-Gal Syndrome Alpha-gal syndrome (AGS), first described in 2009, is associated with a tick bite in which exposed individuals develop IgE antibodies… August 13, 2025
2024 Serious Hazards of Transfusions (SHOT) Report in the U.K. The Royal College of Pathologists in the United Kingdom recently published their annual report for 2024 on the Serious Hazards… August 6, 2025
Machine Learning Model for Estimating Perioperative Transfusion Risks Approximately 20% of RBC units are used for surgeries. Currently, hospitals estimate the risk of perioperative transfusions using historical charts… July 29, 2025
Blood Transfusion Strategies for Major Trauma Early transfusion is associated with reduced morbidity and mortality in major bleeding trauma events. However, the optimal mix of blood… July 22, 2025
Storage Duration Affects Hematological and Metabolic Parameters in Patients with Sickle Cell Disease Red blood cells (RBCs) may be stored for up to 42 days before transfusion; however, over time they may develop… July 16, 2025
Syphilis Infections Among US Blood Donors Syphilis is a sexually transmitted bacterial infection that may also be transmitted by transfusion. Active cases of syphilis are increasing… July 10, 2025
RBCs with Reduced Deformability are Removed from Circulation RBCs, with a diameter of 8 µm, must squeeze through narrow microvascular spaces and endothelial clefts just 1 to 2.5… July 2, 2025
Array-based, comprehensive genotyping for erythroid, platelet, neutrophil and leukocyte antigens Alloimmunization occurs in about 2-5% of transfused patients, even when ABO and RhD blood groups are matched, and rates are… June 26, 2025
Acute Normovolemic Hemodilution Does Not Reduce RBC Transfusions Globally, over two million individuals undergo cardiac surgery annually, and about one third receive at least one unit of allogeneic… June 18, 2025
