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Archive by Topic » News

RBC Transfusions in Neonatal ICUs Above Restrictive Hb Thresholds

In 2020, two randomized clinical trials found that liberal RBC transfusion hemoglobin (Hb) thresholds were non-superior to restrictive thresholds for…

October 23, 2025

Locally Transmitted Malaria in the United States

Currently, half of the world’s population is at risk for malaria. Although malaria was endemic across the southern region of…

October 15, 2025

Global Platelet Transfusion Practices for Patients in the ICU

Platelet transfusion rates for patients in the ICU range from 5% to 15%, but guidelines are primarily based on observational…

October 8, 2025

Plasma Equivalent to Clotting Factor Concentrates for Initial Resuscitation of Patients with Severe Trauma

The incidence of trauma-induced coagulopathy (TIC) is related to the severity of injury and occurs in about 25% of trauma…

October 2, 2025

Personalized Prediction Model of Prophylactic Platelet Transfusions for Preterm Infants

International transfusion guidelines based on one large randomized controlled trial for preterm infants with severe thrombocytopenia (platelet count < 50…

September 24, 2025

Caffeine in Donor Blood Reduces Quality of Stored RBCs

Caffeine, one of the most consumed psychoactive substances worldwide, is a non-selective antagonist of adenosine receptors, including ADORA2B expressed on…

September 16, 2025

Ferritin Levels Needed to Assess Hemoglobin Recovery after Blood Donation

Repeat blood donors are at risk of developing iron deficiency. Premenopausal women lose, on average, 60% of their total iron…

September 10, 2025

Transfusion of RBCs from Cord Blood May Protect Low-Weight Preterm Infants from Severe Retinopathy

RBC transfusions in low-weight preterm infants are associated with retinopathy of prematurity (ROP), a visual impairment that affects their quality…

September 4, 2025

AABB Guidelines Recommend Liberal RBC Transfusion for Patients with Acute Myocardial Infarction

Restrictive transfusion hemoglobin (Hb) thresholds are currently recommended across multiple medical and surgical settings, but the optimal RBC transfusion threshold…

August 27, 2025

Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens

Of the approximately 400 RBC blood group antigens, only ABO/D are matched for routine transfusions. Some RBC blood group antigens…

August 20, 2025

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