No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized… July 17, 2024
RBC Transfusions Guidelines for Very Preterm Infants Most clinical practice guidelines for blood transfusion have focused on adults and limited recommendations are available for children and neonates…. July 9, 2024
Ferritin-Guided Blood Donations Protect Iron Stores in Donors In both North America and Europe, whole blood donors are eligible to donate whole blood every 56 days. Donors lose… July 3, 2024
Donor Deferral Model Evaluates Impact of New Individual Risk Assessment When AIDS emerged in the early 1980s, the risk of acquiring HIV from a transfusion was approximately 1.1%. The U.S…. June 28, 2024
Liberal versus Restrictive Transfusion Strategy for Patients with Traumatic Brain Injury and Anemia While a restrictive RBC transfusion strategy has been shown to be safe and effective for most patients, there is uncertainty… June 19, 2024
Luspatercept Reduces Transfusion-Dependence for Anemic Patients with Myelofibrosis Myelofibrosis is a rare bone marrow cancer characterized by excessive scarring that disrupts the production of red blood cells. Current… June 11, 2024
FDA: Donor Screening of Zika Virus Unnecessary in United States In 2015 and 2016, large outbreaks of the mosquito-borne Zika virus occurred in the Americas. Infection with the Zika virus… June 5, 2024
Tranexamic Acid Treatment Does Not Reduce Hematoma Growth in Patients with Intracerebral Hemorrhage Intracerebral hemorrhage affects approximately 3.4 million individuals worldwide annually. Hematoma growth during intracerebral hemorrhage is associated with significant morbidity and… May 29, 2024
Cold-Stored Platelets Do Not Restore Platelet Function as well as Room-Temperature Platelets The U.S. Food and Drug Administration recently approved cold storage of platelets for up to 14 days for the treatment… May 22, 2024
Recombinant ADAMTS13 Treatment for Congenital Thrombotic Thrombocytopenic Purpura Congenital thrombotic thrombocytopenic purpura (TTP) is a rare disease caused by a severe hereditary deficiency of ADAMTS13, which normally cleaves… May 15, 2024