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Archive by Topic » News

RBCs Regulate Hemostasis Through Platelet-Dependent and -Independent Mechanisms

Red blood cells (RBCs) deliver oxygen to tissues and also contribute to hemostasis and thrombosis through platelet interactions that promote…

October 9, 2024

Liberal Transfusion Threshold of 9-10 g/dL for Patients with Myocardial Infarction

While restrictive transfusion hemoglobin (Hb) thresholds are appropriate for most patients, those with anemia and myocardial infarction (MI) may benefit…

October 2, 2024

Genetic Background of AnWj-Negative Blood Group Deciphered

Of the 45 blood group systems comprising 362 described antigens, only a few high prevalence antigens are not genetically resolved…

September 25, 2024

Donor-Specific Antibody Levels and Platelet Transfusion Response Among Refractory Patients

  Hematology-oncology patients often require multiple platelet transfusions, which can lead to immune-mediated platelet transfusion refractoriness. This condition may necessitate…

September 19, 2024

Global Blood Supply Challenges

The World Health Organization (WHO) considers blood an essential medicine, yet nearly two-thirds of countries—primarily low- and middle-income countries (LMIC)—lack…

September 11, 2024

Prevalence and Trends of Maternal RBC Alloimmunization in the U.S.

Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic…

September 4, 2024

Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients Undergoing Liver Resection

Tranexamic acid is a synthetic compound that prevents fibrin clot degradation and has been shown to reduce blood loss and…

August 27, 2024

Blood Donation Rates Higher in Countries with Higher Healthcare Quality and Expenditure

Most studies on blood donation rates have focused on individual donor behaviors, and little is known about how the quality…

August 21, 2024

Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn

Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules…

August 14, 2024

Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency

Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous…

August 7, 2024

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