Global Platelet Transfusion Practices for Patients in the ICU Platelet transfusion rates for patients in the ICU range from 5% to 15%, but guidelines are primarily based on observational… October 8, 2025
Personalized Prediction Model of Prophylactic Platelet Transfusions for Preterm Infants International transfusion guidelines based on one large randomized controlled trial for preterm infants with severe thrombocytopenia (platelet count < 50… September 24, 2025
Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients with Hematological Malignancies Prophylactic platelet transfusions are common for patients with hematological malignancies and severe hypoproliferative thrombocytopenia. Tranexamic acid, an antifibrinolytic drug, has… January 30, 2025
A New, Simple Proxy to Measure Oxygen Unloading and the Quality of Stored Blood The functional quality of transfused blood depends upon oxygen delivery to the tissues. Oxygen carrying capacity is easily and routinely… January 16, 2025
Quality and Effectiveness of Irradiated Platelets Platelets are often irradiated to inactivate residual lymphocytes and prevent transfusion-associated graft-vs-host disease. As irradiated platelets are widely used, researchers… December 5, 2024
Cold Stored Platelets for Severe Trauma Patients Ever since platelets stored at room temperature were shown to survive longer in circulation than those stored at colder temperatures,… October 31, 2024
Donor-Specific Antibody Levels and Platelet Transfusion Response Among Refractory Patients Hematology-oncology patients often require multiple platelet transfusions, which can lead to immune-mediated platelet transfusion refractoriness. This condition may necessitate… September 19, 2024
Cold-Stored Platelets Do Not Restore Platelet Function as well as Room-Temperature Platelets The U.S. Food and Drug Administration recently approved cold storage of platelets for up to 14 days for the treatment… May 22, 2024
MiPLATE Clinical Trial: Mirasol® Pathogen Reduction Treated Platelets The Mirasol® Pathogen Reduction Technology System (Terumo, BCT, Lakewood, CO) uses a combination of riboflavin (vitamin B2) and UV light… February 13, 2024
Platelet Transfusions and Increased Risk of Death or Neurodevelopmental Impairment in Preterm Infants Preterm infants are at an increased risk for intracranial hemorrhage, as many are thrombocytopenic (<150,000 platelets/µL). Although there is little… February 7, 2024
Platelet Transfusion