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Platelet Transfusion

Donor-Specific Antibody Levels and Platelet Transfusion Response Among Refractory Patients

  Hematology-oncology patients often require multiple platelet transfusions, which can lead to immune-mediated platelet transfusion refractoriness. This condition may necessitate…

September 19, 2024

Cold-Stored Platelets Do Not Restore Platelet Function as well as Room-Temperature Platelets

The U.S. Food and Drug Administration recently approved cold storage of platelets for up to 14 days for the treatment…

May 22, 2024

MiPLATE Clinical Trial: Mirasol® Pathogen Reduction Treated Platelets

The Mirasol® Pathogen Reduction Technology System (Terumo, BCT, Lakewood, CO) uses a combination of riboflavin (vitamin B2) and UV light…

February 13, 2024

Platelet Transfusions and Increased Risk of Death or Neurodevelopmental Impairment in Preterm Infants

Preterm infants are at an increased risk for intracranial hemorrhage, as many are thrombocytopenic (<150,000 platelets/µL). Although there is little…

February 7, 2024

Deep Learning A.I. System for Platelet Management

Platelet inventory management is challenging due to their short shelf-life and fluctuating demand.  Researchers in Germany created a risk assessment…

January 10, 2024

Safety of Platelet and Plasma Transfusions in the COVID-19 Era

By September 2022, 96% of U.S. blood donors had antibodies to SARS-CoV-2 due to infection and/or vaccination.  Some patient advocacy…

December 13, 2023

Pathogen-Reduced Platelet Use and Overall Blood Product Cost Increased

Since 1997, the biennial Department of Health and Human Services’ National Blood and Collection Utilization Survey (NBCUS) has been used…

September 27, 2023

Expanding U.S. Platelet Supply Needed

About 2.5 million units of platelets are transfused each year in the U.S., and data from the National Blood Collection…

June 7, 2023

Randomized Trial of Platelet Transfusions and Risk of Bleeding before CVC Placement

About 18% of all hospitalized patients require central venous catheters (CVC) and is even more common on hematology wards and…

May 31, 2023

Whole Blood Derived Platelet vs. Apheresis Platelets

During the COVID-19 pandemic, the U.S. experienced significant blood product shortages. In 2019, approximately 2.5 million platelet units were collected…

April 12, 2023

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  • Double-knotting Blood Storage Bag Tubing Reduces Contamination

  • Costs of Type & Screen and Crossmatch Laboratory Tests for RBCs Higher in U.S. Compared to U.K.

  • Gene Editing of HBG1 and HBG2 Promotors to Treat β-Thalassemia and Sickle Cell Disease

  • Jehovah’s Witness Governing Body Allows Autologous Transfusions

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