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Platelet Transfusion

Clinical Predictors of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare, life-threatening condition in pregnancy and is the leading cause of intracranial…

November 30, 2022

Prophylactic Tranexamic Acid Does Not Decrease Bleeding or Transfusions in Patients with Hematologic Malignancies

Patients with hematologic malignancies account for 43% of the 2 million platelet doses transfused in the U.S. each year.  Despite…

September 21, 2022

Platelet-Rich Plasma Injections Do Not Improve Ankle Osteoarthritis

Ankle (tibiotalar) osteoarthritis affects approximately 3.4% of adults and is associated with a reduced quality of life.  Effective non-surgical treatments…

November 17, 2021

Pathogen Reduced Platelets are Non-Inferior to Conventional Platelets for Hematology Patients

Results for the PIPER Phase 4 study of psoralen-UVA pathogen reduced platelets (PRPC) (Cerus Corporation) following transfusion were recently presented…

October 28, 2021

Cold Storage Affects Platelet Function and Glycoprotein VI Levels

Maintaining an adequate supply of platelets is laborious and costly since they can only be stored for 5 to 7…

October 20, 2021

RBC and Plasma Transfusions Decreased in the U.S. (2015-2018)

Blood transfusions are one of the most common medical procedures in hospitalized patients, and robust data from randomized clinical trials…

September 28, 2021

REDS-III Study Highlights Need for Pediatric Oncology Transfusion Guidelines

  Pediatric hematology/oncology patients receive a significant proportion of pediatric transfusions.  Data, however, are limited guiding clinical decisions for transfusions…

September 22, 2021

Mean Fluorescence Intensity to Select HLA-Matched Platelets

Over two million units of platelets are transfused each year in the United States—the majority to hematology-oncology patients.  Alloimmunization against…

August 13, 2021

U.S. National Platelet Inventory and Transfusion Practice Survey

Nearly 7,000 units of platelets are needed daily in the U.S., and platelet transfusions increased by 15.8% from 2017 to…

August 3, 2021

Epitope Matched HLA Platelets Are Noninferior to Standard Matched HLA Platelets

Alloimmunization to human leukocyte antigens (HLA) leads to platelet refractoriness, defined as decreased post-transfusion platelet count increments (PCIs), and is…

January 27, 2021

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  • Running Ultra-Long Distances Induces Inflammatory and Oxidative Stress Changes in RBCs

  • Tranexamic Acid for Patients with Hematological Disorders

  • Interventions to Prevent Vasovagal Reactions among Blood Donors

  • Nipocalimab for Severe Hemolytic Disease of the Fetus and Newborn

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