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Platelet Transfusion

Platelet Transfusion Use in the United States

Although RBC transfusions have decreased over the past decade, the demand for platelet transfusions has increased.   In order to better…

December 30, 2019

Mechanisms and Implications of Why Platelet Transfusions May Not Always Be Effective

Platelet transfusions are not always effective at preventing bleeding in patients with inherited and acquired platelet disorders such as Glanzmann’s…

December 18, 2019

Thrombosomes (Lyophilized Platelets) Appear Safe in Phase 1 Trial

  Data from a phase 1, open-label, multi-center safety trial of lyophilized platelets were recently presented at the 2019 AABB…

October 24, 2019

FDA Guidance to Control for Bacterial Contamination in Platelets

The U.S. Food and Drug Administration (FDA) has issued final guidance to reduce bacterial contamination of platelets stored at room…

October 9, 2019

RBC Alloimmunization is a Predictor of HLA Alloimmunization

Alloantibodies to the human leukocyte antigens (HLA) or red blood cells (RBCs) can develop after exposure to alloantigens such as…

July 17, 2019

Restrictive Platelet Transfusions Superior in Preterm Infants with Thrombocytopenia

Greater than 10% of babies are born prematurely in Europe and the United States, and many of these infants have…

November 13, 2018

Cryopreserved Platelets Are Safe and Prevent Bleeding

Cryopreservation of platelets could drastically simplify storage of platelets, especially for difficult locations such as combat zones, trauma centers, and…

September 26, 2018

Presence of Cell-free Nucleic Acids in Blood Products

Cell-free nucleic acids (CFNAs) are often present in plasma. A new study tested whether CFNAs are also present and active…

July 25, 2018

Pathogen Reduction Technologies and Hemostatic Efficacy of Platelets

Pathogen reduction technologies (PRTs) for platelets inactivate known and unknown viruses, bacteria, and parasites in addition to inactivating white blood…

July 18, 2018

Platelet Counts Decrease during Pregnancy but Severe Thrombocytopenia is Rare

  Gestational thrombocytopenia affects 5-10% of women with uncomplicated pregnancies. In order to gain a better understanding of the normal…

July 10, 2018

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