Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules… August 14, 2024
Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous… August 7, 2024
Carnitine Metabolism Associated with Red Blood Cell Hemolysis Red blood cells can be stored up to 42 days, after which they progressively develop a series of storage lesions—partly… July 25, 2024
RBC Transfusions Guidelines for Very Preterm Infants Most clinical practice guidelines for blood transfusion have focused on adults and limited recommendations are available for children and neonates…. July 9, 2024
Liberal versus Restrictive Transfusion Strategy for Patients with Traumatic Brain Injury and Anemia While a restrictive RBC transfusion strategy has been shown to be safe and effective for most patients, there is uncertainty… June 19, 2024
Luspatercept Reduces Transfusion-Dependence for Anemic Patients with Myelofibrosis Myelofibrosis is a rare bone marrow cancer characterized by excessive scarring that disrupts the production of red blood cells. Current… June 11, 2024
Study Finds No Association Between RBC Transfusions and Necrotizing Enterocolitis Necrotizing enterocolitis (NEC) affects approximately 1 in 1000 premature babies, usually two to six weeks after birth, and accounts for… May 7, 2024
Gut Microbe Exoglycosidases Target ABO Blood Group Antigens to Generate ABO-Universal Blood The ABO blood group is the most immunogenic group of blood antigens, and incompatible mismatched ABO-blood is among the most… May 1, 2024
Transfusion Patterns After CAR T-Cell Therapy for Large B-Cell Lymphoma Three different types of chimeric antigen receptor (CAR) T-cell therapies have been approved to treat refractory or relapsed large B-cell… April 10, 2024
Stored RBCs May Have Slower Oxygen Unloading for Tissue Oxygen delivery to tissues is dependent on blood flow, the oxygen carrying capacity of the RBCs (related to hemoglobin levels),… March 27, 2024