Transfusion Patterns After CAR T-Cell Therapy for Large B-Cell Lymphoma Three different types of chimeric antigen receptor (CAR) T-cell therapies have been approved to treat refractory or relapsed large B-cell… April 10, 2024
Stored RBCs May Have Slower Oxygen Unloading for Tissue Oxygen delivery to tissues is dependent on blood flow, the oxygen carrying capacity of the RBCs (related to hemoglobin levels),… March 27, 2024
Recombinant Erythropoietin for Patients with Autoimmune Hemolytic Anemia Autoimmune hemolytic anemia (AIHA) is a rare disorder with multiple etiologies and usually presents as anemia with hemolysis. Initial treatments… March 21, 2024
Strategies for Blood Deserts Every country in sub-Saharan Africa and South Asia, along with some other low-income and middle-income countries often experience blood shortages…. February 28, 2024
Low Alloimmunization Risk if No Antibodies Formed during First 20 RBC Transfused Units RBC transfusions are critical for many patients with sickle cell disease. Patients are at risk, however, of developing alloantibodies, which… January 4, 2024
Thalidomide Reduces Bleeding and Blood Transfusions in Patients with Small-Intestinal Angiodysplasia Small-intestinal angiodysplasia (SIA), characterized by vascular malformation in the GI tract, is the most common cause of recurrent bleeding in… December 27, 2023
Darbepoetin Alfa Reduces RBC Transfusions in Infants with HDFN Treated with Intrauterine Transfusions Hemolytic disease of the fetus and newborn (HDFN) is a severe disorder caused by maternal antibodies against fetal RBC antigens… December 6, 2023
Restrictive or Liberal Transfusion Thresholds for Patients with Myocardial Infarctions While restrictive transfusion thresholds are beneficial for most patients and reduce blood use by 50%, but transfusion guidelines state there… November 15, 2023
Small-Volume Blood Collection Tubes Reduce Transfusion Patients in the intensive care unit (ICU) often have multiple blood draws daily, which typically amount to approximately one… November 1, 2023
High Variability in ICU Transfusion Practices Globally The International Point Prevalence Study of Intensive Care Unit Transfusion Practices (InPUT) is a prospective cohort study that included 3643… October 18, 2023