Study Finds No Association Between RBC Transfusions and Necrotizing Enterocolitis Necrotizing enterocolitis (NEC) affects approximately 1 in 1000 premature babies, usually two to six weeks after birth, and accounts for… May 7, 2024
Gut Microbe Exoglycosidases Target ABO Blood Group Antigens to Generate ABO-Universal Blood The ABO blood group is the most immunogenic group of blood antigens, and incompatible mismatched ABO-blood is among the most… May 1, 2024
Transfusion Patterns After CAR T-Cell Therapy for Large B-Cell Lymphoma Three different types of chimeric antigen receptor (CAR) T-cell therapies have been approved to treat refractory or relapsed large B-cell… April 10, 2024
Stored RBCs May Have Slower Oxygen Unloading for Tissue Oxygen delivery to tissues is dependent on blood flow, the oxygen carrying capacity of the RBCs (related to hemoglobin levels),… March 27, 2024
Recombinant Erythropoietin for Patients with Autoimmune Hemolytic Anemia Autoimmune hemolytic anemia (AIHA) is a rare disorder with multiple etiologies and usually presents as anemia with hemolysis. Initial treatments… March 21, 2024
Strategies for Blood Deserts Every country in sub-Saharan Africa and South Asia, along with some other low-income and middle-income countries often experience blood shortages…. February 28, 2024
Low Alloimmunization Risk if No Antibodies Formed during First 20 RBC Transfused Units RBC transfusions are critical for many patients with sickle cell disease. Patients are at risk, however, of developing alloantibodies, which… January 4, 2024
Thalidomide Reduces Bleeding and Blood Transfusions in Patients with Small-Intestinal Angiodysplasia Small-intestinal angiodysplasia (SIA), characterized by vascular malformation in the GI tract, is the most common cause of recurrent bleeding in… December 27, 2023
Darbepoetin Alfa Reduces RBC Transfusions in Infants with HDFN Treated with Intrauterine Transfusions Hemolytic disease of the fetus and newborn (HDFN) is a severe disorder caused by maternal antibodies against fetal RBC antigens… December 6, 2023
Restrictive or Liberal Transfusion Thresholds for Patients with Myocardial Infarctions While restrictive transfusion thresholds are beneficial for most patients and reduce blood use by 50%, but transfusion guidelines state there… November 15, 2023