Wide Variations in Treatments and Outcomes Globally in Hemolytic Disease of the Fetus and Newborn Hemolytic disease of the fetus and newborn (HDFN) is a life-threatening disorder in which maternal alloantibodies destroy fetal and neonatal… November 19, 2024
RHD Genotyping May Enable D-positive RBC Units to be Transfused to Patients with Anti-D Patients with sickle cell disease (SCD) often require chronic red blood cell exchanges. The American Society for Hematology recommends matching… November 13, 2024
Intravenous vs Oral Iron for Pregnant Women in Africa Worldwide, almost 40% of all pregnant women are anemic (hemoglobin < 11 g/dL) with the percentage rising to around 50%… November 7, 2024
Liberal Transfusion Thresholds for Patients with Acute Brain Injury Over the past 25 years, >45 randomized clinical trials have shown that a restrictive transfusion strategy is best for most… October 17, 2024
RBCs Regulate Hemostasis Through Platelet-Dependent and -Independent Mechanisms Red blood cells (RBCs) deliver oxygen to tissues and also contribute to hemostasis and thrombosis through platelet interactions that promote… October 9, 2024
Liberal Transfusion Threshold of 9-10 g/dL for Patients with Myocardial Infarction While restrictive transfusion hemoglobin (Hb) thresholds are appropriate for most patients, those with anemia and myocardial infarction (MI) may benefit… October 2, 2024
Prevalence and Trends of Maternal RBC Alloimmunization in the U.S. Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic… September 4, 2024
Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients Undergoing Liver Resection Tranexamic acid is a synthetic compound that prevents fibrin clot degradation and has been shown to reduce blood loss and… August 27, 2024
Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules… August 14, 2024
Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous… August 7, 2024
RBC Transfusion