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RBC Transfusion

Liberal Transfusion Threshold of 9-10 g/dL for Patients with Myocardial Infarction

While restrictive transfusion hemoglobin (Hb) thresholds are appropriate for most patients, those with anemia and myocardial infarction (MI) may benefit…

October 2, 2024

Prevalence and Trends of Maternal RBC Alloimmunization in the U.S.

Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic…

September 4, 2024

Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients Undergoing Liver Resection

Tranexamic acid is a synthetic compound that prevents fibrin clot degradation and has been shown to reduce blood loss and…

August 27, 2024

Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn

Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules…

August 14, 2024

Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency

Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous…

August 7, 2024

Carnitine Metabolism Associated with Red Blood Cell Hemolysis

Red blood cells can be stored up to 42 days, after which they progressively develop a series of storage lesions—partly…

July 25, 2024

RBC Transfusions Guidelines for Very Preterm Infants

Most clinical practice guidelines for blood transfusion have focused on adults and limited recommendations are available for children and neonates….

July 9, 2024

Liberal versus Restrictive Transfusion Strategy for Patients with Traumatic Brain Injury and Anemia

While a restrictive RBC transfusion strategy has been shown to be safe and effective for most patients, there is uncertainty…

June 19, 2024

Luspatercept Reduces Transfusion-Dependence for Anemic Patients with Myelofibrosis

Myelofibrosis is a rare bone marrow cancer characterized by excessive scarring that disrupts the production of red blood cells. Current…

June 11, 2024

Study Finds No Association Between RBC Transfusions and Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) affects approximately 1 in 1000 premature babies, usually two to six weeks after birth, and accounts for…

May 7, 2024

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