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Search Results for: Sickle cell

RBC Transfusions Reduce Fatigability in Hospitalized Patients with Anemia

In order to determine if red blood cell (RBC) transfusions improve quality of life for hospitalized patients with anemia, researchers…

December 1, 2020

Risk Factors for Hyperhemolysis Syndrome Identified

Hyperhemolysis Syndrome (HS) is a rare, potentially fatal condition characterized by the development of severe anemia after transfusion in which…

October 16, 2019

Immunogenicity of MMR Vaccine in Chronically Transfused Pediatric Patients

Both the American Advisory Committee on Immunization Practices (ACIP) and the Canadian immunization guide recommend delaying live vaccine immunizations for…

September 10, 2019

CRISPR-Gene Editing Uses for Transfusion Medicine

Clustered regularly interspaced short palindromic repeats (CRISPR) and Cas proteins evolved as part of the prokaryotes adaptive immune system. Cas…

April 18, 2019

Locus on Chromosome 5 Associated with Alloimmunization

Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with…

January 9, 2019

Genetic Variation in the Fc-gamma Receptor Gene is Associated with Protection against RBC Alloimmunization

 Genetic variation in the Fc-ɣ receptor gene has been shown to be associated with some auto- and alloimmune diseases. Researchers…

November 16, 2017

VIDEO: The Present Global Anemia Burden

Today we will be discussing the global burden of anemia. Anemia is characterized by a decrease in red blood cells…

February 28, 2014

Randomized Trial Demonstrates that Hydroxyurea is Not Effective as Transfusion in Preventing Strokes

Published in the journal Blood, Ware and Helms report results from the Stroke With Transfusions Changing to Hydroxyurea (SWiTCH) randomized…

July 20, 2012

New Techniques Identify Oxidative Lesions on Stored RBCs

Stored red blood cells (RBCs) undergo morphologic and biochemical changes with time. In a recently published study in Blood, researchers…

September 28, 2016

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