Antigen Density on Surface of RBCs a Factor in RBC Clearance in Incompatible Transfusions Select patients with chronic anemia and sickle cell disease require recurrent transfusions and are at risk for alloimmunization and potentially… February 3, 2021
CRISPR-Cas9 Gene Editing and Lentiviral Gene Therapy Hold Promise to Treat Transfusion Dependent β-Globin Hemoglobinopathies Both transfusion-dependent β-thalassemia (TDT) and sickle cell disease (SCD) are common monogenetic diseases caused by mutations in the gene encoding… December 15, 2020
RBC Transfusions Reduce Fatigability in Hospitalized Patients with Anemia In order to determine if red blood cell (RBC) transfusions improve quality of life for hospitalized patients with anemia, researchers… December 1, 2020
Risk Factors for Hyperhemolysis Syndrome Identified Hyperhemolysis Syndrome (HS) is a rare, potentially fatal condition characterized by the development of severe anemia after transfusion in which… October 16, 2019
Immunogenicity of MMR Vaccine in Chronically Transfused Pediatric Patients Both the American Advisory Committee on Immunization Practices (ACIP) and the Canadian immunization guide recommend delaying live vaccine immunizations for… September 10, 2019
CRISPR-Gene Editing Uses for Transfusion Medicine Clustered regularly interspaced short palindromic repeats (CRISPR) and Cas proteins evolved as part of the prokaryotes adaptive immune system. Cas… April 18, 2019
Locus on Chromosome 5 Associated with Alloimmunization Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with… January 9, 2019
Genetic Variation in the Fc-gamma Receptor Gene is Associated with Protection against RBC Alloimmunization Genetic variation in the Fc-ɣ receptor gene has been shown to be associated with some auto- and alloimmune diseases. Researchers… November 16, 2017
VIDEO: The Present Global Anemia Burden Today we will be discussing the global burden of anemia. Anemia is characterized by a decrease in red blood cells… February 28, 2014
Randomized Trial Demonstrates that Hydroxyurea is Not Effective as Transfusion in Preventing Strokes Published in the journal Blood, Ware and Helms report results from the Stroke With Transfusions Changing to Hydroxyurea (SWiTCH) randomized… July 20, 2012