Donor Age, Not Donor Sex, Is the Primary Factor Influencing RBC Deformability RBC deformability—the ability to alter shape and squeeze through capillaries and other microvascular tissues—is essential for oxygen delivery to tissues… March 5, 2025
Using Machine Learning Models to Predict the Likelihood of a Transfusion Over 85 million units of RBCs are transfused annually worldwide, and the decision to transfuse is usually based on a… February 26, 2025
Plasma Transfusion Practices in ICUs Globally Platelet transfusion guidelines discourage prophylactic plasma transfusion for non-bleeding patients, yet findings from the International Point Prevalence Study of Intensive… February 18, 2025
Antibodies to Amustaline/Glutathione Pathogen Reduced RBCs While the U.S. FDA has approved the use of pathogen reduction (PR) technologies for platelets and plasma, it has not… February 12, 2025
Traditional Chinese Herbs Not Effective for Intracerebral Hemorrhage: A Randomized Trial Herbs have been used in traditional Chinese medicine for centuries, but the effectiveness of many of these treatments remain unknown…. February 6, 2025
Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients with Hematological Malignancies Prophylactic platelet transfusions are common for patients with hematological malignancies and severe hypoproliferative thrombocytopenia. Tranexamic acid, an antifibrinolytic drug, has… January 30, 2025
New FDA Draft Guidance to Reduce Transfusion-Transmitted Malaria Malaria, caused by five Plasmodium species (e.g., P. falciparum), is recognized as a significant transfusion-transmitted infection by the U.S. Food… January 22, 2025
A New, Simple Proxy to Measure Oxygen Unloading and the Quality of Stored Blood The functional quality of transfused blood depends upon oxygen delivery to the tissues. Oxygen carrying capacity is easily and routinely… January 16, 2025
Hypovolemic Phlebotomy Reduces Transfusions During Liver Surgery About 15% to 20% of patients undergoing liver resections require RBC transfusions. Current guidelines propose a number of options to… January 8, 2025
Phase 1 Trial Results for Lentiviral Gene Therapy for Patients with Hemophilia A Hemophilia A is a X-linked disorder characterized by less than 1% of blood clotting Factor VIII in the blood and… January 1, 2025
