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Archive by Topic » News

Caffeine in Donor Blood Reduces Quality of Stored RBCs

Caffeine, one of the most consumed psychoactive substances worldwide, is a non-selective antagonist of adenosine receptors, including ADORA2B expressed on…

September 16, 2025

Ferritin Levels Needed to Assess Hemoglobin Recovery after Blood Donation

Repeat blood donors are at risk of developing iron deficiency. Premenopausal women lose, on average, 60% of their total iron…

September 10, 2025

Transfusion of RBCs from Cord Blood May Protect Low-Weight Preterm Infants from Severe Retinopathy

RBC transfusions in low-weight preterm infants are associated with retinopathy of prematurity (ROP), a visual impairment that affects their quality…

September 4, 2025

AABB Guidelines Recommend Liberal RBC Transfusion for Patients with Acute Myocardial Infarction

Restrictive transfusion hemoglobin (Hb) thresholds are currently recommended across multiple medical and surgical settings, but the optimal RBC transfusion threshold…

August 27, 2025

Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens

Of the approximately 400 RBC blood group antigens, only ABO/D are matched for routine transfusions. Some RBC blood group antigens…

August 20, 2025

Transfusion-related Alpha-Gal Syndrome

Alpha-gal syndrome (AGS), first described in 2009, is associated with a tick bite in which exposed individuals develop IgE antibodies…

August 13, 2025

2024 Serious Hazards of Transfusions (SHOT) Report in the U.K.

The Royal College of Pathologists in the United Kingdom recently published their annual report for 2024 on the Serious Hazards…

August 6, 2025

Machine Learning Model for Estimating Perioperative Transfusion Risks

Approximately 20% of RBC units are used for surgeries. Currently, hospitals estimate the risk of perioperative transfusions using historical charts…

July 29, 2025

Blood Transfusion Strategies for Major Trauma

Early transfusion is associated with reduced morbidity and mortality in major bleeding trauma events. However, the optimal mix of blood…

July 22, 2025

Storage Duration Affects Hematological and Metabolic Parameters in Patients with Sickle Cell Disease

Red blood cells (RBCs) may be stored for up to 42 days before transfusion; however, over time they may develop…

July 16, 2025

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  • Blood Donation and Improved Cardiometabolic Health

  • Mitochondrial DNA Acts as a “First Hit” for Antibody-Mediated TRALI

  • Liberal or Restrictive Transfusion Thresholds for Surgery Patients with High Cardiac Risk

  • Iron Supplementation for Blood Donors Based on Ferritin Levels

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