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Search Results for: Sickle cell

Delayed Hemolytic Transfusion Reactions are Under Diagnosed in Patients with Sickle Cell Disease

Red blood cell transfusions are often used to treat patients with sickle cell disease (SCD), and these patients are at…

May 1, 2019

Matching RH Genotypes for Patients with Sickle Cell Disease

RH antigens are encoded by two highly polymorphic genes, RHD and RHCE.  Homologous recombination and novel polymorphism have resulted in…

September 19, 2018

Red Cell Exchange for Patients with Sickle Cell Disease: an AABB Report

The Therapeutic Apheresis Subsection of the AABB, composed of 15 practicing apheresis physicians from 14 institutions, recently summarized how they…

September 12, 2018

New Assessment Criteria to Diagnose and Manage Delayed Hemolytic Transfusion Reactions in Sickle Cell Patients

Many patients with sickle cell disease (SCD) require chronic transfusions and are at risk for life-threatening delayed hemolytic transfusion reactions…

May 23, 2018

Crizanlizumab May Help Sickle Cell Patients Prevent Pain Crises

Vaso-occlusive crisis—sickle cell pain related crisis—is the primary cause for hospital visits for sickle cell patients. Although the etiology of…

December 7, 2016

Mutating Haematopoietic Stem Cells May Cure Sickle Cell Disease

Sickle cell disease and β-thalassaemia are caused by mutations in the β -globin gene. Previous studies have shown that transplants…

November 16, 2016

Blood Transfusions Reduce Mortality in Patients with Sickle Cell Anemia

Simple and exchange blood transfusions are standard care for prevention of recurrent strokes in patients with sickle cell anemia.  Blood…

May 11, 2016

Eculizumab Treatment May Be Beneficial For Treating Hemolysis Transfusion Reactions in Patients with Sickle Cell Disease

Delayed hemolytic transfusion reactions (DHTR) in patients with sickle cell disease can lead to multiple organ failure and may be…

March 2, 2016

Hematopoietic Stem Cell Transplants for Patients with Sickle Cell Disease

Data presented at the 57th American Society of Hematology Annual Meeting and Exposition in December in Orlando, Florida suggests that…

December 29, 2015

VIDEO: New Guidelines for Treatment of Sickle Cell Disease

Today we’ll be discussing a new set of guidelines for treating patients with sickle cell disease recently published in JAMA…

September 30, 2014

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